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Entry type
Status
Per-residue features
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Protein
GBC15066.1
Length
598 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain268 - 492
- Dbl homology (DH) domain (IPR000219)
-
Domain432 - 582
- PH domain-like (IPR011993)
- Pleckstrin homology domain (IPR001849)
- PH domain-like (IPR011993)
1
100
200
300
400
500
598
Detailed signature matches

Unintegrated signatures
-
cd00160 (RhoGEF)281 - 469
-
cd00821 (PH)500 - 572
-
mobidb-lite (disord...)58 - 209246 - 275
Residue annotation
-
GTPase interaction...287EGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)291TGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)392EGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)420NGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)421SGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)424SGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)425LGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)427IGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)428QGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)431PGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)432RGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)435LGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)436LGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)439AGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)465AGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)469NGTPase interaction site
287E, 291T, 392E, 420N, 421S, 424S, 425L, 427I, 428Q, 431P, 432R, 435L, 436L, 439A, 465A, 469N
CDD
cd00160 (RhoGEF)
GO term prediction
Biological Process
GO:0035023 regulation of Rho protein signal transduction
Molecular Function
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Cellular Component
None predicted.