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Protein

GBC15043.1

Length

1,620 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
Domain
Repeat

1 200 400 600 800 1000 1200 1400 1620

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

IPR000719

Protein kinase domain

SM00220 (serkin_6)
PS50011 (PROTEIN_KI...)
PF00069 (Pkinase)

IPR016024

Armadillo-type fold

SSF48371 (ARM repeat)

IPR017986

WD40-repeat-containing domain

SSF50978 (WD40 repe...)
PS50294 (WD_REPEATS...)

IPR021133

HEAT, type 2

PS50077 (HEAT_REPEAT)

IPR001680

WD40 repeat

SM00320 (WD40_4)
PS50082 (WD_REPEATS_2)
PF00400 (WD40)

IPR008271

Serine/threonine-protein kinase, active site

PS00108 (PROTEIN_KI...)

no IPR

Unintegrated signatures

cd13980 (STKc_Vps15)
mobidb-lite (disord...)

Residue annotation

ATP binding site c...
active site cd13980

191R

active site
33L, 34S, 35S, 36A, 37R, 41T, 52V, 54K, 86F, 102R, 103Q, 104F, 105F, 108S, 110Y, 147D, 149K, 151E, 152N, 154L, 165D, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

192R

active site
33L, 34S, 35S, 36A, 37R, 41T, 52V, 54K, 86F, 102R, 103Q, 104F, 105F, 108S, 110Y, 147D, 149K, 151E, 152N, 154L, 165D, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

193T

active site
33L, 34S, 35S, 36A, 37R, 41T, 52V, 54K, 86F, 102R, 103Q, 104F, 105F, 108S, 110Y, 147D, 149K, 151E, 152N, 154L, 165D, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

194C

active site
33L, 34S, 35S, 36A, 37R, 41T, 52V, 54K, 86F, 102R, 103Q, 104F, 105F, 108S, 110Y, 147D, 149K, 151E, 152N, 154L, 165D, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)
polypeptide substr...

37R

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

108S

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

110Y

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

147D

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

149K

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

151E

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

168G

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

191R

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

192R

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

193T

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

194C

polypeptide substrate binding site
37R, 108S, 110Y, 147D, 149K, 151E, 168G, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)
activation loop (A...

164A

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

165D

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

166F

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

167A

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

168G

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

169Y

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

170K

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

171P

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

172T

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

173Y

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

174L

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

175P

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

176E

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

177D

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

178N

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

179P

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

180A

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

181D

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

182F

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

183S

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

184F

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

185F

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

186F

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

191R

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

192R

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

193T

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

194C

activation loop (A-loop)
164A, 165D, 166F, 167A, 168G, 169Y, 170K, 171P, 172T, 173Y, 174L, 175P, 176E, 177D, 178N, 179P, 180A, 181D, 182F, 183S, 184F, 185F, 186F, 191R, 192R, 193T, 194C
CDD
cd13980 (STKc_Vps15)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component