GBC14953.1

Protein

Length

302 amino acids

Protein family membership

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (IPR004529)

Domains and repeats

Domain
14 - 288
Phenylalanyl-tRNA synthetase (IPR002319)
Domain
34 - 295
Aminoacyl-tRNA synthetase, class II (IPR006195)

1 50 100 150 200 250 302

Detailed signature matches

IPR004529

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
1. TIGR00468
  
  2 - 292
  
  TIGRFAMs
  TIGR00468 (TIGR00468)
IPR002319

Phenylalanyl-tRNA synthetase
1. PF01409 (tRNA-synt_2d)
  
  14 - 288
  
  Pfam
  PF01409 (tRNA-synt_2d)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  34 - 295
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)

no IPR

Unintegrated signatures

SSF55681 (Class II ...)

14 - 285

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)
cd00496 (PheRS_alph...)

30 - 287

CDD
cd00496 (PheRS_alpha_core)

Residue annotation

dimer interface cd...

30H

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

33M

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

36R

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

37E

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

44F

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

49E

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

50E

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

52P

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

53T

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

54N

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

72Q

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

77D

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

81T

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

82F

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

83F

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

84I

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

85K

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

86D

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

140M

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

151P

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

152V

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

153K

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

157I

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

159R

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

161F

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

163N

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

171L

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

188L

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

189G

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

190D

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

192I

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

193G

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

211P

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

218E

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

219P

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

220S

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

222E

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

243R

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

244P

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

282L

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

284H

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

285K

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)

286V

dimer interface
30H, 33M, 36R, 37E, 44F, 49E, 50E, 52P, 53T, 54N, 72Q, 77D, 81T, 82F, 83F, 84I, 85K, 86D, 140M, 151P, 152V, 153K, 157I, 159R, 161F, 163N, 171L, 188L, 189G, 190D, 192I, 193G, 211P, 218E, 219P, 220S, 222E, 243R, 244P, 282L, 284H, 285K, 286V
CDD
cd00496 (PheRS_alpha_core)
motif 1 cd00496

48F

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

49E

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

50E

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

51M

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

52P

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

53T

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)

54N

motif 1
48F, 49E, 50E, 51M, 52P, 53T, 54N
CDD
cd00496 (PheRS_alpha_core)
active site cd00496

77D

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

78A

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

79H

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

132H

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

134T

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

137S

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

162R

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

164E

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

169T

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

170H

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

171L

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

174F

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

176Q

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

178E

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

214N

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

216Y

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

217T

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

235E

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

236I

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

237G

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

238N

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

239S

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

240G

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

261W

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

262G

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

263L

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

264G

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

267R

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)

278I

active site
77D, 78A, 79H, 132H, 134T, 137S, 162R, 164E, 169T, 170H, 171L, 174F, 176Q, 178E, 214N, 216Y, 217T, 235E, 236I, 237G, 238N, 239S, 240G, 261W, 262G, 263L, 264G, 267R, 278I
CDD
cd00496 (PheRS_alpha_core)
motif 2 cd00496

161F

motif 2
161F, 162R, 163N, 164E
CDD
cd00496 (PheRS_alpha_core)

162R

motif 2
161F, 162R, 163N, 164E
CDD
cd00496 (PheRS_alpha_core)

163N

motif 2
161F, 162R, 163N, 164E
CDD
cd00496 (PheRS_alpha_core)

164E

motif 2
161F, 162R, 163N, 164E
CDD
cd00496 (PheRS_alpha_core)
motif 3 cd00496

262G

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

263L

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

264G

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

265L

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

266E

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

267R

motif 3
262G, 263L, 264G, 265L, 266E, 267R
CDD
cd00496 (PheRS_alpha_core)

GO term prediction

Biological Process

GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

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Entry type

Status

Per-residue features