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Protein

GBC13908.1

Length

357 amino acids

Protein family membership

Phosphotyrosyl phosphatase activator, PTPA (IPR004327)

Domains and repeats

None predicted.

Detailed signature matches

IPR004327

Phosphotyrosyl phosphatase activator, PTPA

cd04087 (PTPA)

32 - 296

CDD
cd04087 (PTPA)
PF03095 (PTPA)

11 - 300

Pfam
PF03095 (PTPA)
PIRSF016325 (PTPA)

1 - 350

PIRSF
PIRSF016325 (PTPA)

no IPR

Unintegrated signatures

SSF140984 (PTPA-like)

8 - 303

SUPERFAMILY
SSF140984 (PTPA-like)

Residue annotation

peptide-induced di...

79V

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

88N

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

132R

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

184W

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

185L

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

187P

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

190S

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

191H

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

193V

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

199Y

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

247V

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

249T

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

250A

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

254W

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)

291Q

peptide-induced dimer interface
79V, 88N, 132R, 184W, 185L, 187P, 190S, 191H, 193V, 199Y, 247V, 249T, 250A, 254W, 291Q
CDD
cd04087 (PTPA)
ATP binding site c...

132R

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

134D

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

136G

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

137T

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

138G

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

139H

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

188A

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

189G

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

190S

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

288P

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

289I

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

291Q

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

292H

ATP binding site
132R, 134D, 136G, 137T, 138G, 139H, 188A, 189G, 190S, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)
putative interacti...

132R

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

134D

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

136G

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

137T

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

138G

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

139H

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

187P

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

188A

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

197D

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

198D

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

199Y

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

201F

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

262I

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

265V

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

271V

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

275M

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

278M

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

282E

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

286K

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

288P

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

289I

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

291Q

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)

292H

putative interaction site
132R, 134D, 136G, 137T, 138G, 139H, 187P, 188A, 197D, 198D, 199Y, 201F, 262I, 265V, 271V, 275M, 278M, 282E, 286K, 288P, 289I, 291Q, 292H
CDD
cd04087 (PTPA)
putative PP2A bind...

193V

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)

254W

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)

265V

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)

274G

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)

278M

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)

286K

putative PP2A binding surface
193V, 254W, 265V, 274G, 278M, 286K
CDD
cd04087 (PTPA)
peptide binding po...

193V

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

194W

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

257P

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

258M

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

261D

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

262I

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

265V

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

274G

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

275M

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

285G

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

286K

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

287L

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

288P

peptide binding pocket
193V, 194W, 257P, 258M, 261D, 262I, 265V, 274G, 275M, 285G, 286K, 287L, 288P
CDD
cd04087 (PTPA)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0019211 phosphatase activator activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC13908.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component