GBC12325.1

Protein

Length

1,434 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1,075 - 1,390
NADP-dependent oxidoreductase domain (IPR023210)

1 200 400 600 800 1000 1200 1434

Detailed signature matches

IPR023210

NADP-dependent oxidoreductase domain
1. PF00248 (Aldo_ket_red)
  
  1,087 - 1,390
  
  Pfam
  PF00248 (Aldo_ket_red)
2. cd06660 (Aldo_ket_red)
  
  1,075 - 1,390
  
  CDD
  cd06660 (Aldo_ket_red)
3. SSF51430 (NAD(P)-li...)
  
  1,075 - 1,390
  
  SUPERFAMILY
  SSF51430 (NAD(P)-linked oxidoreductase)

no IPR

Unintegrated signatures

Coil

287 - 307

COILS
Coil (Coil)

787 - 807

COILS
Coil (Coil)

Residue annotation

active site cd06660

1,091G

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,092A

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,093L

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,124D

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,129Y

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,154K

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,202H

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,203F

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,232S

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,233D

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,258Q

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,286W

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,287G

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,288V

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,289V

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,290A

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,291E

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,342V

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,359L

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,360I

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,361G

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,362A

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,367Q

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,370E

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)

1,371N

active site
1,091G, 1,092A, 1,093L, 1,124D, 1,129Y, 1,154K, 1,202H, 1,203F, 1,232S, 1,233D, 1,258Q, 1,286W, 1,287G, 1,288V, 1,289V, 1,290A, 1,291E, 1,342V, 1,359L, 1,360I, 1,361G, 1,362A, 1,367Q, 1,370E, 1,371N
CDD
cd06660 (Aldo_ket_red)
catalytic tetrad c...

1,124D

catalytic tetrad
1,124D, 1,129Y, 1,154K, 1,202H
CDD
cd06660 (Aldo_ket_red)

1,129Y

catalytic tetrad
1,124D, 1,129Y, 1,154K, 1,202H
CDD
cd06660 (Aldo_ket_red)

1,154K

catalytic tetrad
1,124D, 1,129Y, 1,154K, 1,202H
CDD
cd06660 (Aldo_ket_red)

1,202H

catalytic tetrad
1,124D, 1,129Y, 1,154K, 1,202H
CDD
cd06660 (Aldo_ket_red)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

GBC12325.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component