GBC12142.1 | g23533.t1 | RIR_0107500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12144.1 | g23535.t1 | RIR_0107700 | specific transcriptional repressor | - | OG0000027 | - | - | - | - | - | - | - | - |
GBC12145.1 | g23536.t1 | RIR_0107800 | myb-like transcription factor | - | OG0000136 | - | - | - | - | - | - | - | - |
GBC12146.1 | JEMT01029746.1_cds_EXX50983.1_29049 | RIR_0107810 | JEMT01029746.1_cds_EXX50983.1_29049 | - | - | - | - | - | - | - | - | - | - |
GBC12147.1 | g23537.t1 | RIR_0107900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12150.1 | g23539.t1 | RIR_0108100 | hypothetical protein | - | OG0000034 | - | - | - | - | - | - | - | - |
GBC12151.1 | g23540.t1 | RIR_0108200 | hypothetical protein | - | OG0000034 | - | - | - | - | - | - | - | - |
GBC12155.1 | JEMT01020612.1_cds_EXX65751.1_14277 | RIR_0108330 | JEMT01020612.1_cds_EXX65751.1_14277 | - | - | - | - | - | - | - | - | - | - |
GBC12163.1 | g23549.t1 | RIR_0109100 | hypothetical protein | - | OG0000384 | - | - | - | - | - | - | - | - |
GBC12164.1 | g23550.t1 | RIR_0109200 | hypothetical protein | - | OG0000384 | - | - | - | - | - | - | - | - |
GBC12165.1 | g23551.t1 | RIR_0109300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12166.1 | g23552.t1 | RIR_0109400 | hypothetical protein | - | OG0000080 | - | - | - | - | - | - | - | - |
GBC12167.1 | g23553.t1 | RIR_0109500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12168.1 | g23554.t1 | RIR_0109600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12170.1 | g23556.t1 | RIR_0109800 | helicase | - | - | - | - | - | - | - | - | - | - |
GBC12172.1 | g23558.t1 | RIR_0110000 | retrovirus-related protein | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12174.1 | g23560.t1 | RIR_0110200 | hypothetical protein | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12178.1 | g14441.t1 | RIR_0110600 | RNA-directed DNA polymerase from mobile element | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12179.1 | g14442.t1 | RIR_0110700 | RNA-directed DNA polymerase from mobile element | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12182.1 | g3954.t1 | RIR_0111000 | copia-type polyprotein | - | OG0000031 | - | - | - | - | - | - | - | - |
GBC12184.1 | g3956.t1 | RIR_0111200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12187.1 | g3959.t1 | RIR_0111500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12192.1 | g3964.t1 | RIR_0112000 | putative protein-primed b-family DNA polymerase | - | - | - | - | - | - | - | - | - | - |
GBC12193.1 | g3965.t1 | RIR_0112100 | d5-like helicase-primase | - | OG0000364 | - | - | - | - | - | - | - | - |
GBC12195.1 | g3967.t1 | RIR_0112300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12197.1 | g3969.t1 | RIR_0112500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12203.1 | g3975.t1 | RIR_0113100 | zinc finger bed domain-containing protein | - | - | - | - | - | - | - | - | - | - |
GBC12205.1 | g3977.t1 | RIR_0113300 | d5-like helicase-primase | - | OG0000364 | - | - | - | - | - | - | - | - |
GBC12207.1 | g3979.t1 | RIR_0113500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12209.1 | g3981.t1 | RIR_0113700 | ATP-dependent DNA helicase pif1-like | - | OG0000037 | YML061C | 50 | 9.00E-25 | "DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells" | AN5278 | 25.54 | 2.00E-17 | "Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance" |
GBC12210.1 | g3982.t1 | RIR_0113800 | serine-threonine protein kinase | - | OG0000000 | YOR231W | 32.17 | 1.00E-13 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication" | AN4385 | 30.83 | 8.00E-14 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12211.1 | g3983.t1 | RIR_0113900 | protein kinase | - | - | YOR231W | 29.81 | 3.00E-13 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication" | AN5973 | 25.96 | 6.00E-13 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12212.1 | g3984.t1 | RIR_0114000 | conserved eukaryotic mitochondrial protein | - | OG0002066 | YLR454W | 22.81 | 5.00E-115 | "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" | AN7348 | 33.57 | 0 | "Ortholog of A. fumigatus Af293 : Afu2g16420, A. niger CBS 513.88 : An15g06820, A. oryzae RIB40 : AO090102000221, Aspergillus wentii : Aspwe1_0108539 and Aspergillus sydowii : Aspsy1_0027034" |
GBC12213.1 | g3985.t1 | RIR_0114100 | hmg-box transcription factor | - | OG0000027 | - | - | - | - | - | - | - | - |
GBC12214.1 | JEMT01026635.1_cds_EXX58689.1_21338 | RIR_0114110 | JEMT01026635.1_cds_EXX58689.1_21338 | - | - | - | - | - | - | - | - | - | - |
GBC12215.1 | g3986.t1 | RIR_0114200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12216.1 | g3987.t1 | RIR_0114300 | Unconventional prefoldin RPB5 interactor 1 | - | OG0004413 | - | - | - | - | - | - | - | - |
GBC12217.1 | g3988.t1 | RIR_0114400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12218.1 | g3989.t1 | RIR_0114500 | aaap amino acid permease | - | OG0003686 | - | - | - | - | - | - | - | - |
GBC12221.1 | g3991.t1 | RIR_0114700 | salt-inducible protein kinase | - | OG0000000 | YNL298W | 32.52 | 1.00E-15 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN5674 | 30.2 | 1.00E-13 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12223.1 | g3993.t1 | RIR_0114900 | protein kinase | - | OG0000000 | YAR019C | 25.11 | 1.00E-12 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN4385 | 30.6 | 7.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12224.1 | g3994.t1 | RIR_0115000 | pyrrolo-quinoline quinone repeat-containing | - | - | - | - | - | - | - | - | - | - |
GBC12225.1 | g3995.t1 | RIR_0115100 | hypothetical protein | - | OG0005890 | - | - | - | - | - | - | - | - |
GBC12226.1 | g3996.t1 | RIR_0115200 | protein kinase | - | - | YOL113W | 29.57 | 9.00E-13 | "Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication" | AN9504 | 30.71 | 3.00E-12 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12229.1 | g3998.t1 | RIR_0115400 | putative serine/threonine-protein | - | - | YNL298W | 31.1 | 5.00E-12 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN9504 | 29.29 | 2.00E-11 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12230.1 | g3999.t1 | RIR_0115500 | salt-inducible protein kinase | - | - | YHL007C | 28.77 | 1.00E-11 | "Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family" | - | - | - | - |
GBC12231.1 | g4000.t1 | RIR_0115600 | protein kinase | - | OG0001131 | YNL298W | 31.82 | 8.00E-14 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN5674 | 28.17 | 3.00E-12 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12233.1 | g4002.t1 | RIR_0115800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12234.1 | g4003.t1 | RIR_0115900 | protein kinase | - | OG0001131 | YMR001C | 27.64 | 3.00E-14 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN5973 | 30.77 | 5.00E-11 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12236.1 | g4005.t1 | RIR_0116100 | hypothetical protein | - | OG0001574 | - | - | - | - | - | - | - | - |
GBC12237.1 | g4006.t1 | RIR_0116200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12238.1 | g4007.t1 | RIR_0116300 | protein kinase | - | - | YPL203W | 32.62 | 2.00E-13 | cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia | AN7737 | 28.02 | 2.00E-11 | Ortholog(s) have protein serine/threonine kinase activity |
GBC12239.1 | g4008.t1 | RIR_0116400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12240.1 | g4009.t1 | RIR_0116500 | spindle assembly checkpoint component mad1 | - | - | - | - | - | - | - | - | - | - |
GBC12244.1 | g4012.t1 | RIR_0116800 | protein kinase | - | OG0000000 | YPL141C | 28.43 | 2.00E-11 | "Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication" | - | - | - | - |
GBC12246.1 | g4013.t1 | RIR_0116900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12248.1 | g4014.t1 | RIR_0117000 | protein kinase | - | - | YNL298W | 27.08 | 1.00E-11 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN5973 | 28.66 | 4.00E-11 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12249.1 | g4015.t1 | RIR_0117100 | zinc finger bed domain-containing protein | - | - | - | - | - | - | - | - | - | - |
GBC12250.1 | g4016.t1 | RIR_0117200 | protein kinase domain containing protein | - | - | - | - | - | - | - | - | - | - |
GBC12251.1 | g4017.t1 | RIR_0117300 | serine/threonine-protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC12252.1 | g4018.t1 | RIR_0117400 | protein kinase | - | - | YNL298W | 31.79 | 9.00E-13 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN7737 | 30.29 | 2.00E-11 | Ortholog(s) have protein serine/threonine kinase activity |
GBC12253.1 | g4019.t1 | RIR_0117500 | protein kinase | - | - | YMR104C | 32.45 | 8.00E-13 | "Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication" | AN5973 | 31.94 | 2.00E-13 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12254.1 | g4020.t1 | RIR_0117600 | serine-threonine protein kinase | - | - | YHL007C | 29.81 | 1.00E-11 | "Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family" | AN5674 | 29.88 | 6.00E-13 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12255.1 | g4021.t1 | RIR_0117700 | protein kinase | - | OG0000248 | YOL113W | 29.81 | 4.00E-13 | "Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication" | AN5674 | 30.2 | 2.00E-13 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12256.1 | g4022.t1 | RIR_0117800 | protein kinase | - | - | YPL209C | 30.94 | 5.00E-12 | "Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest" | AN5973 | 30.07 | 3.00E-11 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12257.1 | g4023.t1 | RIR_0117900 | hypothetical protein | - | OG0000205 | - | - | - | - | - | - | - | - |
GBC12258.1 | g4024.t1 | RIR_0118000 | microtubule-associated protein futsch | - | - | - | - | - | - | - | - | - | - |
GBC12259.1 | g4025.t1 | RIR_0118100 | receptor-interacting serine/threonine-protein | - | - | - | - | - | - | AN6339 | 24 | 7.00E-11 | Essential protein kinase; mutants form brown pigmented microcolonies with polarity defects |
GBC12260.1 | g4026.t1 | RIR_0118200 | "protein kinase, putative" | - | - | YPL209C | 28.49 | 4.00E-13 | "Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest" | AN5674 | 27.52 | 4.00E-12 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12261.1 | g4027.t1 | RIR_0118300 | Endopolyphosphatase | - | OG0001027 | YDR452W | 42.42 | 2.00E-77 | Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer; relocalizes from vacuole to cytoplasm upon DNA replication stress | AN1148 | 42.67 | 2.00E-82 | "Ortholog(s) have endopolyphosphatase activity, exopolyphosphatase activity, role in polyphosphate catabolic process and cytosol, fungal-type vacuole membrane, nucleus localization" |
GBC12262.1 | g4028.t1 | RIR_0118400 | specific transcriptional repressor | - | OG0000027 | - | - | - | - | - | - | - | - |
GBC12264.1 | g4029.t1 | RIR_0118500 | "phosphate abc transporter, phosphate-binding" | - | - | - | - | - | - | - | - | - | - |
GBC12267.1 | g4032.t1 | RIR_0118800 | serine/threonine protein kinase | - | - | YPL140C | 26.27 | 8.00E-19 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication" | AN5815 | 26.6 | 2.00E-17 | Aurora protein serine/threonine kinase |
GBC12269.1 | g4033.t1 | RIR_0118900 | serine/threonine protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC12271.1 | Tis13_24813 | RIR_0119010 | Tis13_24813 | - | - | - | - | - | - | - | - | - | - |
GBC12272.1 | g4035.t1 | RIR_0119100 | "keratin, type I cytoskeletal 13-like" | - | - | - | - | - | - | - | - | - | - |
GBC12274.1 | g4036.t1 | RIR_0119200 | "Cytochrome P450, family 3, subfamily A" | - | OG0000007 | YMR015C | 24.21 | 4.00E-12 | C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs | AN3272 | 26.34 | 1.00E-20 | Putative cytochrome P450 |
GBC12275.1 | g4037.t1 | RIR_0119300 | cytochrome p450 | - | OG0000007 | YMR015C | 23.98 | 1.00E-12 | C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs | AN1601 | 29.59 | 1.00E-21 | Putative cytochrome P450; O-methylsterigmatocystin oxidoreductase with a predicted role in sterigmatocystin/aflatoxin biosynthesis |
GBC12276.1 | g4038.t1 | RIR_0119400 | protein far1-related sequence 11-like isoform | - | OG0000030 | - | - | - | - | - | - | - | - |
GBC12277.1 | g4039.t1 | RIR_0119500 | protein far1-related sequence 11-like isoform | - | OG0000030 | - | - | - | - | - | - | - | - |
GBC12279.1 | g4040.t1 | RIR_0119600 | hypothetical protein | - | OG0000620 | - | - | - | - | - | - | - | - |
GBC12280.1 | g4041.t1 | RIR_0119700 | salt-inducible protein kinase | - | - | YPL140C | 25.27 | 2.00E-14 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication" | AN5815 | 26.49 | 1.00E-14 | Aurora protein serine/threonine kinase |
GBC12281.1 | g4042.t1 | RIR_0119800 | protein kinase | - | - | YPL203W | 26.85 | 9.00E-14 | cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia | AN4385 | 29.86 | 1.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12283.1 | g4044.t1 | RIR_0120000 | protein kinase | - | - | YHL007C | 25.36 | 6.00E-14 | "Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family" | AN4385 | 30.46 | 2.00E-15 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12285.1 | g4046.t1 | RIR_0120200 | serine/threonine protein kinase | - | - | YNL298W | 29.81 | 8.00E-15 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN4385 | 30.2 | 1.00E-15 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12287.1 | g4048.t1 | RIR_0120400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12288.1 | g4049.t1 | RIR_0120500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12290.1 | g4051.t1 | RIR_0120700 | protein kinase | - | - | YNL298W | 33.85 | 2.00E-14 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN4385 | 28.68 | 1.00E-12 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12292.1 | g4052.t1 | RIR_0120800 | hypothetical protein | - | OG0000026 | - | - | - | - | - | - | - | - |
GBC12293.1 | g4053.t1 | RIR_0120900 | zn-finger domain-containing protein | - | OG0000026 | - | - | - | - | - | - | - | - |
GBC12296.1 | g4056.t1 | RIR_0121200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12298.1 | g4057.t1 | RIR_0121300 | putative zinc finger domain-containing protein | - | OG0000011 | - | - | - | - | AN2009 | 33.33 | 8.00E-37 | "Ortholog(s) have role in conidiophore development, conidium formation, hyphal growth" |
GBC12299.1 | g4058.t1 | RIR_0121400 | transmembrane protein | - | OG0002166 | - | - | - | - | - | - | - | - |
GBC12300.1 | g4059.t1 | RIR_0121500 | SEL1 protein | - | OG0000000 | YDL203C | 28.16 | 8.00E-15 | Protein that functions in the cell wall integrity pathway; functions upstream of Pkc1p; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria | AN0810 | 26.19 | 1.00E-24 | Protein with a predicted role in ER-associated protein degradation |
GBC12301.1 | g4060.t1 | RIR_0121600 | serine/threonine protein kinase | - | - | YPL153C | 28.98 | 1.00E-16 | DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxia | AN4385 | 23.92 | 8.00E-17 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12302.1 | JEMT01012489.1_cds_EXX75226.1_4803 | RIR_0121610 | JEMT01012489.1_cds_EXX75226.1_4803 | - | OG0002166 | - | - | - | - | - | - | - | - |
GBC12303.1 | Tis13_4297 | RIR_0121620 | Tis13_4297 | - | - | - | - | - | - | - | - | - | - |
GBC12304.1 | Tis13_10739 | RIR_0121630 | Tis13_10739 | - | - | - | - | - | - | - | - | - | - |
GBC12305.1 | Tis13_14448 | RIR_0121640 | Tis13_14448 | - | OG0000338 | - | - | - | - | - | - | - | - |
GBC12306.1 | g4061.t1 | RIR_0121700 | semaphorin-3f-like | - | OG0000005 | - | - | - | - | - | - | - | - |
GBC12307.1 | g4062.t1 | RIR_0121800 | bis(5'-adenosyl)-triphosphatase-like | - | OG0000005 | - | - | - | - | - | - | - | - |
GBC12308.1 | g4063.t1 | RIR_0121900 | serine/threonine protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC12309.1 | g4063.t2 | RIR_0121900 | serine/threonine protein kinase | - | - | - | - | - | - | AN5973 | 26.67 | 2.00E-11 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12310.1 | g4064.t1 | RIR_0122000 | serine/threonine-protein kinase | - | - | YAR019C | 26.45 | 3.00E-12 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | - | - | - | - |
GBC12311.1 | g4065.t1 | RIR_0122100 | cell wall beta-glucan synthesis family protein | - | OG0002411 | - | - | - | - | - | - | - | - |
GBC12312.1 | g4066.t1 | RIR_0122200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12313.1 | g4067.t1 | RIR_0122300 | aaap amino acid permease | - | OG0003686 | - | - | - | - | - | - | - | - |
GBC12314.1 | g4068.t1 | RIR_0122400 | protein kinase | - | OG0000000 | YOL016C | 33.04 | 9.00E-13 | "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication" | AN7737 | 32.61 | 2.00E-11 | Ortholog(s) have protein serine/threonine kinase activity |
GBC12315.1 | g4068.t2 | RIR_0122400 | protein kinase | - | OG0000000 | YOL016C | 33.04 | 1.00E-12 | "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication" | AN7737 | 32.61 | 1.00E-11 | Ortholog(s) have protein serine/threonine kinase activity |
GBC12316.1 | g4069.t1 | RIR_0122500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12317.1 | g4070.t1 | RIR_0122600 | protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC12318.1 | g4071.t1 | RIR_0122700 | hypothetical protein | - | OG0000080 | - | - | - | - | - | - | - | - |
GBC12319.1 | g4072.t1 | RIR_0122800 | Peptide-methionine-S-oxide reductase | - | OG0001592 | YER042W | 44.19 | 7.00E-48 | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease | AN10562 | 57.8 | 4.00E-72 | Putative methionine sulfoxide reductase with a predicted role in the reduction of methionine sulfoxide to methionine |
GBC12320.1 | g4073.t1 | RIR_0122900 | transmembrane protein | - | - | - | - | - | - | - | - | - | - |
GBC12321.1 | g4074.t1 | RIR_0123000 | serine/threonine protein kinase | - | OG0000000 | YLR362W | 24.75 | 6.00E-14 | "Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress" | AN4887 | 29.33 | 2.00E-15 | "Putative mitogen-activated protein kinase kinase kinase (MAPKKK); inviable mutant arrests as branched germlings, remediated by NaCl or sucrose" |
GBC12324.1 | g4075.t1 | RIR_0123100 | membrane protein | - | OG0002166 | - | - | - | - | - | - | - | - |
GBC12325.1 | g4076.t1 | RIR_0123200 | aryl-alcohol dehydrogenase aad14 | - | OG0000094 | YNL331C | 35.44 | 6.00E-60 | "Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family" | AN5887 | 36.73 | 3.00E-63 | Predicted GTPase activating protein |
GBC12326.1 | g4077.t1 | RIR_0123300 | reverse transcriptase | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12327.1 | g4078.t1 | RIR_0123400 | protein kinase | - | - | YPL203W | 25.69 | 8.00E-13 | cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia | AN4385 | 29.58 | 3.00E-12 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12330.1 | g4080.t1 | RIR_0123600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12331.1 | g4081.t1 | RIR_0123700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12332.1 | g4082.t1 | RIR_0123800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12333.1 | g4083.t1 | RIR_0123900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12334.1 | g4084.t1 | RIR_0124000 | CENP-b protein 1 | - | OG0000010 | - | - | - | - | - | - | - | - |
GBC12335.1 | g4085.t1 | RIR_0124100 | hypothetical protein | - | OG0000010 | - | - | - | - | - | - | - | - |
GBC12336.1 | g4086.t1 | RIR_0124200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12337.1 | g4087.t1 | RIR_0124300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12338.1 | g4088.t1 | RIR_0124400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12339.1 | g4089.t1 | RIR_0124500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12340.1 | Tis13_96288 | RIR_0124510 | Tis13_96288 | - | - | - | - | - | - | - | - | - | - |
GBC12341.1 | g4090.t1 | RIR_0124600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12342.1 | g4091.t1 | RIR_0124700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12343.1 | g4092.t1 | RIR_0124800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12344.1 | g4093.t1 | RIR_0124900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12345.1 | g4094.t1 | RIR_0125000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12346.1 | g4095.t1 | RIR_0125100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12347.1 | g4096.t1 | RIR_0125200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12348.1 | g4097.t1 | RIR_0125300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12349.1 | g4098.t1 | RIR_0125400 | Golgi phosphoprotein 3 | - | OG0001252 | YDR372C | 47.46 | 3.00E-83 | "Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33" | AN5705 | 56.52 | 2.00E-99 | Has domain(s) with predicted phosphatidylinositol-4-phosphate binding activity |
GBC12352.1 | g4099.t1 | RIR_0125500 | endopeptidase | - | OG0000148 | YPL154C | 33.74 | 1.00E-42 | "Vacuolar aspartyl protease (proteinase A); required for posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; plays a protective role in acetic acid induced apoptosis; synthesized as a zymogen, self-activates" | AN4422 | 36.48 | 4.00E-54 | Putative aspartic-type endopeptidase; predicted glycosylphosphatidylinositol (GPI)-anchored protein |
GBC12353.1 | g4100.t1 | RIR_0125600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12354.1 | g4101.t1 | RIR_0125700 | putative Putative ammonium permease ATO3 | - | OG0000645 | YNR002C | 45.61 | 6.00E-40 | "Putative transmembrane protein involved in export of ammonia; ammonia is a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Y. lipolytica Gpr1p; ATO2 has a paralog, ADY2, that arose from the whole genome duplication" | AN5226 | 35.29 | 3.00E-26 | "Acetate permease, involved in acetate uptake; has similarity to GPR1/FUN34/YaaH family members; transcript induced by ethanol" |
GBC12355.1 | g4102.t1 | RIR_0125800 | protein kinase | - | OG0000248 | YKL166C | 25.19 | 3.00E-13 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | AN5674 | 26.17 | 4.00E-12 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12357.1 | g4103.t1 | RIR_0125900 | ATP-dependent DNA helicase pif1-like | - | OG0000037 | YML061C | 27.87 | 2.00E-21 | "DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells" | AN6895 | 25.93 | 5.00E-22 | "Has domain(s) with predicted DNA helicase activity and role in DNA repair, telomere maintenance" |
GBC12361.1 | g4107.t1 | RIR_0126300 | reverse transcriptase | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC12363.1 | g4109.t1 | RIR_0126500 | serine/threonine protein kinase | - | OG0000000 | YLR362W | 26.83 | 2.00E-15 | "Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress" | AN4887 | 31.33 | 4.00E-16 | "Putative mitogen-activated protein kinase kinase kinase (MAPKKK); inviable mutant arrests as branched germlings, remediated by NaCl or sucrose" |
GBC12364.1 | g4110.t1 | RIR_0126600 | btb/poz domain-containing protein 19 | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC12365.1 | JEMT01028581.1_cds_EXX54209.1_25820 | RIR_0126610 | JEMT01028581.1_cds_EXX54209.1_25820 | - | OG0000007 | - | - | - | - | - | - | - | - |
GBC12366.1 | g4111.t1 | RIR_0126700 | "protein kinase, putative" | - | - | YKL166C | 28.9 | 7.00E-14 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | AN4385 | 31.16 | 1.00E-12 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12367.1 | g4112.t1 | RIR_0126800 | protein kinase | - | - | YOR231W | 31.47 | 5.00E-14 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication" | AN5973 | 28.93 | 7.00E-14 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC12368.1 | g4113.t1 | RIR_0126900 | mitogen-activated protein kinase kinase kinase | - | OG0000041 | YAR019C | 25 | 2.00E-12 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN5674 | 28.09 | 2.00E-14 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12371.1 | g4114.t1 | RIR_0127000 | serine-enriched protein | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC12372.1 | g4115.t1 | RIR_0127100 | btb/poz domain-containing protein 9-like | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC12373.1 | g4116.t1 | RIR_0127200 | protein kinase | - | OG0000000 | YKL166C | 26.94 | 1.00E-13 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | AN4385 | 31.47 | 2.00E-12 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12374.1 | g4117.t1 | RIR_0127300 | SEL1 protein | - | OG0000000 | YBL061C | 31.58 | 3.00E-20 | "Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication" | AN0810 | 26.09 | 1.00E-30 | Protein with a predicted role in ER-associated protein degradation |
GBC12376.1 | g4118.t2 | RIR_0127400 | putative serine/threonine-protein | - | - | YMR001C | 29.36 | 3.00E-14 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN9504 | 31.3 | 3.00E-12 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12377.1 | g4118.t1 | RIR_0127400 | putative serine/threonine-protein | - | - | YOL016C | 29.07 | 5.00E-15 | "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication" | AN9504 | 31.06 | 6.00E-13 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12378.1 | g4119.t1 | RIR_0127500 | Sentrin-specific protease 1 | - | OG0000270 | YPL020C | 28.18 | 2.00E-12 | Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions | - | - | - | - |
GBC12379.1 | g4120.t1 | RIR_0127600 | "protein kinase, putative" | - | - | YPL209C | 34.04 | 1.00E-12 | "Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest" | AN4385 | 29.55 | 4.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12380.1 | Tis13_23997 | RIR_0127610 | Tis13_23997 | - | - | - | - | - | - | - | - | - | - |
GBC12381.1 | g4121.t1 | RIR_0127700 | serine/threonine-protein kinase | - | - | YKL166C | 26.64 | 4.00E-11 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | AN2412 | 32.73 | 3.00E-11 | Calcium/calmodulin-dependent protein kinase A; essential for growth and nuclear division; expression downregulated by farnesol; transcript upregulated by camptothecin; mutants have a moderate growth defect and increased pigment production |
GBC12382.1 | g4122.t1 | RIR_0127800 | kelch-like protein 17 | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC12383.1 | g4123.t1 | RIR_0127900 | "protein kinase, putative" | - | OG0000000 | YMR001C | 29.89 | 5.00E-13 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | - | - | - | - |
GBC12385.1 | g4125.t1 | RIR_0128100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12386.1 | g4126.t1 | RIR_0128200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12387.1 | g4127.t1 | RIR_0128300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12388.1 | g4128.t2 | RIR_0128400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12389.1 | g4128.t1 | RIR_0128400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12390.1 | g4129.t2 | RIR_0128500 | serine/threonine protein kinase | - | OG0000000 | YDR523C | 27.76 | 4.00E-19 | Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by them | AN10153 | 26.79 | 1.00E-20 | Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl |
GBC12391.1 | g4129.t1 | RIR_0128500 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC12393.1 | g4131.t1 | RIR_0128700 | serine/threonine kinase | - | OG0000000 | YFR014C | 28.1 | 2.00E-14 | "Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication" | AN5674 | 26.97 | 2.00E-12 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12395.1 | g4133.t3 | RIR_0128900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12396.1 | g4133.t2 | RIR_0128900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12397.1 | g4133.t1 | RIR_0128900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12398.1 | g4134.t3 | RIR_0129000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12399.1 | g4134.t4 | RIR_0129000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12400.1 | g4134.t2 | RIR_0129000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12401.1 | g4134.t1 | RIR_0129000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12402.1 | g4134.t5 | RIR_0129000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12403.1 | g4135.t1 | RIR_0129100 | hsp70 family protein | - | OG0000043 | - | - | - | - | AN0866 | 25.22 | 1.00E-28 | "Ortholog of A. nidulans FGSC A4 : AN3519, AN2646, AN0587, AN7370 and A. fumigatus Af293 : Afu1g15200, Afu3g03790, Afu4g14040, Afu5g06900, Afu7g08575" |
GBC12404.1 | g4136.t1 | RIR_0129200 | hsp70 family protein | - | - | - | - | - | - | - | - | - | - |
GBC12405.1 | g4137.t1 | RIR_0129300 | hsp70 family protein | - | OG0000043 | - | - | - | - | AN0587 | 29.66 | 6.00E-23 | Putative Hsp70 family chaperone; transcript is induced by nitrate |
GBC12407.1 | g4138.t1 | RIR_0129400 | serine/threonine protein kinase | - | OG0000078 | YMR104C | 27.09 | 1.00E-14 | "Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication" | AN4385 | 26.42 | 2.00E-17 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12410.1 | g4141.t1 | RIR_0129700 | salt-inducible protein kinase | - | - | YMR001C | 28.89 | 2.00E-15 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN2067 | 33.79 | 2.00E-13 | Predicted PAK (p21-activated kinase) family protein; similar to Saccharomyces cerevisiae Ste20p; mutants have increased pigment production |
GBC12411.1 | g4142.t1 | RIR_0129800 | protein kinase | - | OG0000248 | YAR019C | 27.47 | 2.00E-12 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | - | - | - | - |
GBC12412.1 | g4143.t1 | RIR_0129900 | umta methyltransferase family protein | - | OG0000025 | - | - | - | - | AN5874 | 28.03 | 2.00E-16 | Putative LaeA-like methyltransferase |
GBC12413.1 | g4144.t1 | RIR_0130000 | salt-inducible protein kinase | - | OG0000248 | YOR231W | 27.06 | 6.00E-14 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication" | AN9504 | 32.37 | 3.00E-12 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12414.1 | g4145.t1 | RIR_0130100 | serine-threonine protein kinase | - | OG0000000 | YAR019C | 29.23 | 3.00E-14 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN9504 | 32.09 | 7.00E-12 | Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal |
GBC12415.1 | g4146.t1 | RIR_0130200 | ATP-dependent DNA helicase PIF1 | - | OG0000037 | YML061C | 50 | 6.00E-24 | "DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells" | AN5278 | 25.54 | 5.00E-18 | "Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance" |
GBC12416.1 | g4147.t1 | RIR_0130300 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | AN11074 | 35.86 | 4.00E-29 | Predicted hAT transposon-related ORF |
GBC12419.1 | g4150.t1 | RIR_0130600 | transcriptional factor b3 | - | OG0000062 | - | - | - | - | AN5278 | 35.84 | 0 | "Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance" |
GBC12420.1 | g4151.t1 | RIR_0130700 | probable carboxypeptidase x1 isoform x2 | - | - | - | - | - | - | - | - | - | - |
GBC12421.1 | g4152.t1 | RIR_0130800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12425.1 | g4156.t1 | RIR_0131200 | "protein kinase, putative" | - | OG0000248 | YOL113W | 32.1 | 1.00E-16 | "Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication" | AN5674 | 30.2 | 2.00E-17 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12426.1 | g4157.t1 | RIR_0131300 | GTPase imap family member 8-like | - | OG0004813 | - | - | - | - | - | - | - | - |
GBC12427.1 | g4158.t1 | RIR_0131400 | sonic hedgehog protein a isoform x1 | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC12428.1 | g4159.t1 | RIR_0131500 | GTPase imap family member 7-like | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC12429.1 | g4160.t1 | RIR_0131600 | GTPase imap family member 7-like | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC12430.1 | JEMT01026557.1_cds_EXX58989.1_21046 | RIR_0131610 | JEMT01026557.1_cds_EXX58989.1_21046 | - | - | - | - | - | - | - | - | - | - |
GBC12432.1 | g4162.t1 | RIR_0131800 | retroviral-like aspartic protease 1 | - | OG0000066 | - | - | - | - | - | - | - | - |
GBC12433.1 | g4163.t1 | RIR_0131900 | retrotransposable element | - | OG0000004 | YIL082W-A | 38.12 | 1.00E-70 | "Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" | AN5470 | 34.8 | 3.00E-65 | Predicted gypsy transposon-related ORF |
GBC12434.1 | g4164.t1 | RIR_0132000 | retrotransposable element | - | OG0000004 | YGR109W-B | 24.33 | 8.00E-18 | "Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" | AN10649 | 27.47 | 7.00E-23 | "Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process" |
GBC12436.1 | g4165.t1 | RIR_0132100 | GTPase imap family member 7-like | - | OG0004813 | - | - | - | - | - | - | - | - |
GBC12437.1 | g4166.t1 | RIR_0132200 | GTPase imap family member 4-like | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC12438.1 | g4167.t1 | RIR_0132300 | GTPase imap family member 4 | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC12439.1 | JEMT01028253.1_cds_EXX55268.1_24765 | RIR_0132310 | JEMT01028253.1_cds_EXX55268.1_24765 | - | - | - | - | - | - | - | - | - | - |
GBC12440.1 | g4168.t1 | RIR_0132400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12441.1 | JEMT01028253.1_cds_EXX55269.1_24766 | RIR_0132410 | JEMT01028253.1_cds_EXX55269.1_24766 | - | - | - | - | - | - | - | - | - | - |
GBC12442.1 | g4169.t1 | RIR_0132500 | "protein kinase, putative" | - | OG0000000 | YOR231W | 30.77 | 5.00E-13 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication" | AN4385 | 27.78 | 2.00E-12 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12443.1 | g4170.t1 | RIR_0132600 | protein kinase | - | - | YMR001C | 29.91 | 1.00E-13 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN4385 | 30.77 | 9.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12444.1 | g4171.t1 | RIR_0132700 | putative Sacsin | - | OG0000482 | - | - | - | - | - | - | - | - |
GBC12446.1 | g4173.t1 | RIR_0132900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12447.1 | g4174.t1 | RIR_0133000 | salt-inducible protein kinase | - | OG0000000 | YNL298W | 32.72 | 3.00E-15 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN5674 | 26.9 | 9.00E-13 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12448.1 | g4174.t2 | RIR_0133000 | salt-inducible protein kinase | - | OG0000000 | YNL298W | 32.72 | 3.00E-15 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN5674 | 26.9 | 9.00E-13 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC12449.1 | g4175.t1 | RIR_0133100 | serine/threonine protein kinase | - | OG0000038 | YHR102W | 25.83 | 1.00E-16 | "Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis" | AN11032 | 26.25 | 1.00E-15 | "Protein kinase; mutants are sensitive to NaCl, have a strong growth defect and display defects in septation and conidiation" |
GBC12452.1 | g4178.t1 | RIR_0133400 | "protein kinase, putative" | - | OG0000000 | YAR019C | 26.9 | 6.00E-14 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN4385 | 30.99 | 8.00E-14 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12453.1 | g4179.t1 | RIR_0133500 | protein kinase | - | OG0000000 | YMR001C | 26.15 | 3.00E-12 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN4385 | 31.03 | 2.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12455.1 | g4181.t1 | RIR_0133700 | hypothetical protein | - | OG0004555 | - | - | - | - | - | - | - | - |
GBC12457.1 | g4183.t1 | RIR_0133900 | protein kinase | - | - | YPL140C | 27.88 | 5.00E-12 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication" | AN4385 | 31.65 | 2.00E-11 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12458.1 | g4184.t1 | RIR_0134000 | proteoglycan 4 | - | - | - | - | - | - | - | - | - | - |
GBC12461.1 | g4187.t1 | RIR_0134300 | serine/threonine protein kinase | - | - | YPL153C | 26.92 | 5.00E-15 | DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxia | AN3065 | 32.47 | 7.00E-15 | "Essential Ca2+/calmodulin-dependent protein kinase, required for nuclear division; required for normal timing of NimX activation at G1/S transition" |
GBC12462.1 | g4188.t1 | RIR_0134400 | serine/threonine protein kinase | - | OG0000038 | YHR102W | 25.37 | 2.00E-13 | "Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis" | AN10153 | 24.25 | 3.00E-13 | Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl |
GBC12463.1 | g4189.t1 | RIR_0134500 | wd40 repeat-containing protein | - | - | YAR019C | 29.55 | 2.00E-14 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | - | - | - | - |
GBC12464.1 | g4190.t1 | RIR_0134600 | umta methyltransferase family protein | - | OG0000025 | - | - | - | - | - | - | - | - |
GBC12465.1 | g4191.t1 | RIR_0134700 | protein kinase | - | OG0000248 | YAR019C | 26.49 | 8.00E-13 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN7737 | 31.25 | 1.00E-12 | Ortholog(s) have protein serine/threonine kinase activity |
GBC12466.1 | g4192.t1 | RIR_0134800 | protein kinase | - | - | YKL166C | 30.89 | 3.00E-13 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | AN6305 | 26.34 | 6.00E-11 | cAMP-dependent protein kinase catalytic subunit; cAMP signaling during conidial germination; overlapping functions with SchA; induced by osmotic stress; mutant growth defect remediated by sucrose and NaCl; reduced growth on AVICEL medium |
GBC12468.1 | g4193.t1 | RIR_0134900 | kelch-like protein 17 | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC12469.1 | g4194.t1 | RIR_0135000 | zinc finger mym-type protein 2-like | - | - | - | - | - | - | - | - | - | - |
GBC12470.1 | g4195.t1 | RIR_0135100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12471.1 | g4196.t1 | RIR_0135200 | mitogen-activated protein kinase kinase kinase | - | - | - | - | - | - | - | - | - | - |
GBC12472.1 | g4197.t1 | RIR_0135300 | tkl/lisk/lisk-dd1 protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC12473.1 | JEMT01012764.1_cds_EXX74653.1_5375 | RIR_0135310 | JEMT01012764.1_cds_EXX74653.1_5375 | - | - | - | - | - | - | - | - | - | - |
GBC12474.1 | g4198.t1 | RIR_0135400 | ATP-dependent DNA helicase pif1-like | - | OG0000037 | - | - | - | - | - | - | - | - |
GBC12475.1 | g4199.t1 | RIR_0135500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12476.1 | g4200.t1 | RIR_0135600 | serine-threonine protein kinase | - | OG0000248 | YAR019C | 26.2 | 3.00E-12 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN10153 | 27.92 | 9.00E-11 | Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl |
GBC12477.1 | g4201.t1 | RIR_0135700 | protein kinase | - | OG0000000 | YMR001C | 25.5 | 2.00E-14 | Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate | AN4385 | 31.85 | 8.00E-14 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC12479.1 | g4202.t1 | RIR_0135800 | serine-threonine protein kinase | - | OG0000248 | YKL166C | 37.61 | 2.00E-11 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication" | - | - | - | - |
GBC12481.1 | g4203.t1 | RIR_0135900 | hypothetical protein | - | OG0000464 | - | - | - | - | - | - | - | - |
GBC12482.1 | g4204.t1 | RIR_0136000 | Srm1p | - | OG0000657 | YGL097W | 28.64 | 3.00E-46 | "Nucleotide exchange factor for Gsp1p; localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p" | AN6978 | 31.59 | 4.00E-41 | Putative nucleotide exchange factor involved in nucleocytoplasmic trafficking of macromolecules |
GBC12484.1 | g4206.t1 | RIR_0136200 | "ER organization and biogenesis-related protein," | - | OG0002494 | YDR320C | 28.27 | 4.00E-29 | Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles | AN8798 | 32.26 | 2.00E-44 | "Ortholog of A. fumigatus Af293 : Afu5g09630, A. niger CBS 513.88 : An07g03250, A. oryzae RIB40 : AO090020000592, Aspergillus wentii : Aspwe1_0023820 and Aspergillus sydowii : Aspsy1_0159494" |
GBC12485.1 | g4207.t1 | RIR_0136300 | g-patch domain-containing protein | - | OG0000917 | - | - | - | - | AN3567 | 22.48 | 1.00E-13 | "Ortholog of Aspergillus wentii : Aspwe1_0105538, Aspergillus versicolor : Aspve1_0195944 and Aspergillus sydowii : Aspsy1_0057674" |
GBC12486.1 | g4208.t1 | RIR_0136400 | clathrin-coated vesicle protein | - | OG0002332 | YJL207C | 25.85 | 1.00E-27 | AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene | AN6598 | 31.7 | 0 | "Ortholog(s) have role in endocytosis and endocytic vesicle, nucleus localization" |
GBC12487.1 | g4209.t1 | RIR_0136500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12488.1 | g4210.t1 | RIR_0136600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12489.1 | g4211.t1 | RIR_0136700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12493.1 | g4215.t1 | RIR_0137100 | DNA polymerase | - | OG0000287 | - | - | - | - | - | - | - | - |
GBC12494.1 | g4216.t1 | RIR_0137200 | hypothetical protein | - | OG0000004 | - | - | - | - | - | - | - | - |
GBC12497.1 | g4219.t1 | RIR_0137500 | hypothetical protein | - | OG0000366 | - | - | - | - | - | - | - | - |
GBC12500.1 | g4222.t1 | RIR_0137800 | DNA polymerase epsilon catalytic subunit a | - | OG0000463 | - | - | - | - | AN10755 | 26.05 | 1.00E-10 | "Ortholog(s) have DNA replication origin binding, DNA-directed DNA polymerase activity, chromatin binding, single-stranded DNA binding activity" |
GBC12502.1 | g4224.t1 | RIR_0138000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12504.1 | g4226.t1 | RIR_0138200 | uvr/rep helicase | - | - | - | - | - | - | - | - | - | - |
GBC12505.1 | g4227.t1 | RIR_0138300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12506.1 | g4228.t1 | RIR_0138400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12507.1 | Tis13_105280 | RIR_0138410 | Tis13_105280 | - | - | - | - | - | - | - | - | - | - |
GBC12508.1 | g4229.t1 | RIR_0138500 | hypothetical protein | - | OG0000069 | - | - | - | - | - | - | - | - |
GBC12509.1 | g4230.t1 | RIR_0138600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12510.1 | g4231.t1 | RIR_0138700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12511.1 | g4232.t1 | RIR_0138800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12512.1 | g4233.t1 | RIR_0138900 | hypothetical protein | - | OG0000080 | - | - | - | - | - | - | - | - |
GBC12513.1 | g4234.t1 | RIR_0139000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12514.1 | g4235.t1 | RIR_0139100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12515.1 | g4236.t1 | RIR_0139200 | hypothetical protein | - | OG0000047 | - | - | - | - | - | - | - | - |
GBC12518.1 | g4239.t1 | RIR_0139500 | highly derived d5-like helicase-primase | - | - | - | - | - | - | - | - | - | - |
GBC12519.1 | g4239.t2 | RIR_0139500 | highly derived d5-like helicase-primase | - | - | - | - | - | - | - | - | - | - |
GBC12520.1 | g4240.t1 | RIR_0139600 | serine/threonine protein kinase | - | OG0000001 | YJL095W | 27.67 | 1.00E-12 | MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase | AN10153 | 22.99 | 6.00E-11 | Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl |
GBC12522.1 | g4242.t1 | RIR_0139800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12523.1 | g4243.t1 | RIR_0139900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12524.1 | g4244.t1 | RIR_0140000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12525.1 | g4245.t1 | RIR_0140100 | serine/threonine/tyrosine protein kinase rad53 | - | - | - | - | - | - | - | - | - | - |
GBC12526.1 | g4246.t1 | RIR_0140200 | Galactokinase | - | OG0002442 | YDR009W | 37.05 | 8.00E-108 | "Transcriptional regulator; involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity; GAL3 has a paralog, GAL1, that arose from the whole genome duplication" | AN4957 | 37.14 | 2.00E-115 | Putative galactokinase with a predicted role in galactose and galactitol metabolism |
GBC12527.1 | g4247.t2 | RIR_0140300 | translation regulator | - | OG0000110 | - | - | - | - | - | - | - | - |
GBC12528.1 | g4247.t1 | RIR_0140300 | translation regulator | - | OG0000110 | - | - | - | - | - | - | - | - |
GBC12529.1 | g4248.t1 | RIR_0140400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12530.1 | g4249.t1 | RIR_0140500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12531.1 | g4250.t1 | RIR_0140600 | Phospholipase D1/2 | - | OG0000377 | YKR031C | 57.14 | 7.00E-125 | "Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with ""foot domain"" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions" | AN6712 | 39.44 | 1.00E-166 | Putative phospholipase D; expression upregulated after exposure to farnesol |
GBC12532.1 | g4251.t1 | RIR_0140700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12533.1 | g4252.t1 | RIR_0140800 | umta methyltransferase family protein | - | OG0000025 | - | - | - | - | AN2165 | 31.58 | 1.00E-13 | Putative LaeA-like methyltransferase |
GBC12534.1 | g4253.t1 | RIR_0140900 | Peroxisomal membrane protein 4 | - | OG0003799 | - | - | - | - | AN1483 | 48.95 | 3.00E-53 | "Ortholog of A. fumigatus Af293 : Afu8g04780, A. niger CBS 513.88 : An16g08040, A. oryzae RIB40 : AO090005000669, Aspergillus wentii : Aspwe1_0643990 and Aspergillus sydowii : Aspsy1_0055812" |
GBC12535.1 | g4254.t1 | RIR_0141000 | mitochondrial ribosomal protein subunit l11 | - | OG0002428 | - | - | - | - | - | - | - | - |
GBC12536.1 | g4255.t1 | RIR_0141100 | duf423 protein | - | OG0004101 | - | - | - | - | - | - | - | - |
GBC12537.1 | g4255.t2 | RIR_0141100 | duf423 protein | - | OG0004101 | - | - | - | - | - | - | - | - |
GBC12538.1 | g4256.t1 | RIR_0141200 | DnaJ homolog subfamily B member 4 | - | OG0000067 | YNL007C | 35.02 | 1.00E-29 | Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1 | AN2238 | 37.41 | 6.00E-39 | Has domain(s) with predicted unfolded protein binding activity and role in protein folding |
GBC12539.1 | Tis13_335549 | RIR_0141210 | Tis13_335549 | - | - | - | - | - | - | - | - | - | - |
GBC12540.1 | g4257.t2 | RIR_0141300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12541.1 | g4257.t1 | RIR_0141300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12542.1 | g4258.t1 | RIR_0141400 | hypothetical protein | - | OG0003626 | YNL107W | 39.62 | 6.00E-17 | Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes; may function to antagonize silencing near telomeres; interacts directly with Swc4p; has homology to human leukemogenic protein AF9; contains a YEATS domain | AN10181 | 47.17 | 2.00E-11 | "Ortholog of A. fumigatus Af293 : Afu1g09530, A. niger CBS 513.88 : An08g01090, A. oryzae RIB40 : AO090012000919, Neosartorya fischeri NRRL 181 : NFIA_016080 and Aspergillus wentii : Aspwe1_0036341" |
GBC12543.1 | g4259.t1 | RIR_0141500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12544.1 | g4260.t1 | RIR_0141600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC12549.1 | g4262.t1 | RIR_0141800 | transposase domain-containing protein | - | OG0000002 | - | - | - | - | - | - | - | - |
GBC12550.1 | g4263.t1 | RIR_0141900 | hypothetical protein | - | OG0000002 | - | - | - | - | - | - | - | - |
GBC12552.1 | g4265.t1 | RIR_0142100 | hypothetical protein | - | OG0000002 | - | - | - | - | - | - | - | - |
GBC12553.1 | g4266.t1 | RIR_0142200 | hypothetical protein | - | OG0000002 | - | - | - | - | - | - | - | - |
GBC12557.1 | JEMT01016063.1_cds_EXX71618.1_8411 | RIR_0142510 | JEMT01016063.1_cds_EXX71618.1_8411 | - | - | - | - | - | - | - | - | - | - |
GBC12559.1 | g4271.t1 | RIR_0142700 | CENP-b protein 1 | - | OG0000010 | YDR081C | 21.13 | 1.00E-12 | Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions | AN8717 | 32.04 | 2.00E-48 | "Has domain(s) with predicted DNA binding, nucleic acid binding activity" |
GBC12561.1 | g4273.t1 | RIR_0142900 | hypothetical protein | - | OG0001124 | - | - | - | - | - | - | - | - |
GBC12563.1 | JEMT01018155.1_cds_EXX66941.1_13086 | RIR_0143010 | JEMT01018155.1_cds_EXX66941.1_13086 | - | - | - | - | - | - | - | - | - | - |
GBC12565.1 | g4275.t1 | RIR_0143100 | transposase domain-containing protein | - | OG0000002 | - | - | - | - | - | - | - | - |
GBC12567.1 | g4277.t1 | RIR_0143300 | gastrula zinc finger protein xlcgf46.1 | - | - | - | - | - | - | - | - | - | - |
GBC12568.1 | g4278.t2 | RIR_0143400 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | - | - | - | - |
GBC12569.1 | g4278.t1 | RIR_0143400 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | - | - | - | - |