home > Gene Annotation List

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NCBI IDProteinIDLocusTagProductIDCazyIDOrthGroupIDSGD IDidentevalAnnotationASpGD IDidentEvalAnnotation
GBC12142.1g23533.t1RIR_0107500hypothetical protein----------
GBC12144.1g23535.t1RIR_0107700specific transcriptional repressor-OG0000027--------
GBC12145.1g23536.t1RIR_0107800myb-like transcription factor-OG0000136--------
GBC12146.1JEMT01029746.1_cds_EXX50983.1_29049RIR_0107810JEMT01029746.1_cds_EXX50983.1_29049----------
GBC12147.1g23537.t1RIR_0107900hypothetical protein----------
GBC12150.1g23539.t1RIR_0108100hypothetical protein-OG0000034--------
GBC12151.1g23540.t1RIR_0108200hypothetical protein-OG0000034--------
GBC12155.1JEMT01020612.1_cds_EXX65751.1_14277RIR_0108330JEMT01020612.1_cds_EXX65751.1_14277----------
GBC12163.1g23549.t1RIR_0109100hypothetical protein-OG0000384--------
GBC12164.1g23550.t1RIR_0109200hypothetical protein-OG0000384--------
GBC12165.1g23551.t1RIR_0109300hypothetical protein----------
GBC12166.1g23552.t1RIR_0109400hypothetical protein-OG0000080--------
GBC12167.1g23553.t1RIR_0109500hypothetical protein----------
GBC12168.1g23554.t1RIR_0109600hypothetical protein----------
GBC12170.1g23556.t1RIR_0109800helicase----------
GBC12172.1g23558.t1RIR_0110000retrovirus-related protein-OG0000001--------
GBC12174.1g23560.t1RIR_0110200hypothetical protein-OG0000001--------
GBC12178.1g14441.t1RIR_0110600RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12179.1g14442.t1RIR_0110700RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12182.1g3954.t1RIR_0111000copia-type polyprotein-OG0000031--------
GBC12184.1g3956.t1RIR_0111200hypothetical protein----------
GBC12187.1g3959.t1RIR_0111500hypothetical protein----------
GBC12192.1g3964.t1RIR_0112000putative protein-primed b-family DNA polymerase----------
GBC12193.1g3965.t1RIR_0112100d5-like helicase-primase-OG0000364--------
GBC12195.1g3967.t1RIR_0112300hypothetical protein----------
GBC12197.1g3969.t1RIR_0112500hypothetical protein----------
GBC12203.1g3975.t1RIR_0113100zinc finger bed domain-containing protein----------
GBC12205.1g3977.t1RIR_0113300d5-like helicase-primase-OG0000364--------
GBC12207.1g3979.t1RIR_0113500hypothetical protein----------
GBC12209.1g3981.t1RIR_0113700ATP-dependent DNA helicase pif1-like-OG0000037YML061C509.00E-25"DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells"AN527825.542.00E-17"Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance"
GBC12210.1g3982.t1RIR_0113800serine-threonine protein kinase-OG0000000YOR231W32.171.00E-13"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN438530.838.00E-14"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12211.1g3983.t1RIR_0113900protein kinase--YOR231W29.813.00E-13"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN597325.966.00E-13Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12212.1g3984.t1RIR_0114000conserved eukaryotic mitochondrial protein-OG0002066YLR454W22.815.00E-115"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"AN734833.570"Ortholog of A. fumigatus Af293 : Afu2g16420, A. niger CBS 513.88 : An15g06820, A. oryzae RIB40 : AO090102000221, Aspergillus wentii : Aspwe1_0108539 and Aspergillus sydowii : Aspsy1_0027034"
GBC12213.1g3985.t1RIR_0114100hmg-box transcription factor-OG0000027--------
GBC12214.1JEMT01026635.1_cds_EXX58689.1_21338RIR_0114110JEMT01026635.1_cds_EXX58689.1_21338----------
GBC12215.1g3986.t1RIR_0114200hypothetical protein----------
GBC12216.1g3987.t1RIR_0114300Unconventional prefoldin RPB5 interactor 1-OG0004413--------
GBC12217.1g3988.t1RIR_0114400hypothetical protein----------
GBC12218.1g3989.t1RIR_0114500aaap amino acid permease-OG0003686--------
GBC12221.1g3991.t1RIR_0114700salt-inducible protein kinase-OG0000000YNL298W32.521.00E-15"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN567430.21.00E-13"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12223.1g3993.t1RIR_0114900protein kinase-OG0000000YAR019C25.111.00E-12Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN438530.67.00E-13"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12224.1g3994.t1RIR_0115000pyrrolo-quinoline quinone repeat-containing----------
GBC12225.1g3995.t1RIR_0115100hypothetical protein-OG0005890--------
GBC12226.1g3996.t1RIR_0115200protein kinase--YOL113W29.579.00E-13"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN950430.713.00E-12Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12229.1g3998.t1RIR_0115400putative serine/threonine-protein--YNL298W31.15.00E-12"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN950429.292.00E-11Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12230.1g3999.t1RIR_0115500salt-inducible protein kinase--YHL007C28.771.00E-11"Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family"----
GBC12231.1g4000.t1RIR_0115600protein kinase-OG0001131YNL298W31.828.00E-14"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN567428.173.00E-12"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12233.1g4002.t1RIR_0115800hypothetical protein----------
GBC12234.1g4003.t1RIR_0115900protein kinase-OG0001131YMR001C27.643.00E-14Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN597330.775.00E-11Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12236.1g4005.t1RIR_0116100hypothetical protein-OG0001574--------
GBC12237.1g4006.t1RIR_0116200hypothetical protein----------
GBC12238.1g4007.t1RIR_0116300protein kinase--YPL203W32.622.00E-13cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxiaAN773728.022.00E-11Ortholog(s) have protein serine/threonine kinase activity
GBC12239.1g4008.t1RIR_0116400hypothetical protein----------
GBC12240.1g4009.t1RIR_0116500spindle assembly checkpoint component mad1----------
GBC12244.1g4012.t1RIR_0116800protein kinase-OG0000000YPL141C28.432.00E-11"Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication"----
GBC12246.1g4013.t1RIR_0116900hypothetical protein----------
GBC12248.1g4014.t1RIR_0117000protein kinase--YNL298W27.081.00E-11"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN597328.664.00E-11Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12249.1g4015.t1RIR_0117100zinc finger bed domain-containing protein----------
GBC12250.1g4016.t1RIR_0117200protein kinase domain containing protein----------
GBC12251.1g4017.t1RIR_0117300serine/threonine-protein kinase----------
GBC12252.1g4018.t1RIR_0117400protein kinase--YNL298W31.799.00E-13"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN773730.292.00E-11Ortholog(s) have protein serine/threonine kinase activity
GBC12253.1g4019.t1RIR_0117500protein kinase--YMR104C32.458.00E-13"Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication"AN597331.942.00E-13Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12254.1g4020.t1RIR_0117600serine-threonine protein kinase--YHL007C29.811.00E-11"Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family"AN567429.886.00E-13"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12255.1g4021.t1RIR_0117700protein kinase-OG0000248YOL113W29.814.00E-13"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN567430.22.00E-13"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12256.1g4022.t1RIR_0117800protein kinase--YPL209C30.945.00E-12"Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest"AN597330.073.00E-11Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12257.1g4023.t1RIR_0117900hypothetical protein-OG0000205--------
GBC12258.1g4024.t1RIR_0118000microtubule-associated protein futsch----------
GBC12259.1g4025.t1RIR_0118100receptor-interacting serine/threonine-protein------AN6339247.00E-11Essential protein kinase; mutants form brown pigmented microcolonies with polarity defects
GBC12260.1g4026.t1RIR_0118200"protein kinase, putative"--YPL209C28.494.00E-13"Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest"AN567427.524.00E-12"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12261.1g4027.t1RIR_0118300Endopolyphosphatase-OG0001027YDR452W42.422.00E-77Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer; relocalizes from vacuole to cytoplasm upon DNA replication stressAN114842.672.00E-82"Ortholog(s) have endopolyphosphatase activity, exopolyphosphatase activity, role in polyphosphate catabolic process and cytosol, fungal-type vacuole membrane, nucleus localization"
GBC12262.1g4028.t1RIR_0118400specific transcriptional repressor-OG0000027--------
GBC12264.1g4029.t1RIR_0118500"phosphate abc transporter, phosphate-binding"----------
GBC12267.1g4032.t1RIR_0118800serine/threonine protein kinase--YPL140C26.278.00E-19"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"AN581526.62.00E-17Aurora protein serine/threonine kinase
GBC12269.1g4033.t1RIR_0118900serine/threonine protein kinase----------
GBC12271.1Tis13_24813RIR_0119010Tis13_24813----------
GBC12272.1g4035.t1RIR_0119100"keratin, type I cytoskeletal 13-like"----------
GBC12274.1g4036.t1RIR_0119200"Cytochrome P450, family 3, subfamily A"-OG0000007YMR015C24.214.00E-12C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN327226.341.00E-20Putative cytochrome P450
GBC12275.1g4037.t1RIR_0119300cytochrome p450-OG0000007YMR015C23.981.00E-12C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN160129.591.00E-21Putative cytochrome P450; O-methylsterigmatocystin oxidoreductase with a predicted role in sterigmatocystin/aflatoxin biosynthesis
GBC12276.1g4038.t1RIR_0119400protein far1-related sequence 11-like isoform-OG0000030--------
GBC12277.1g4039.t1RIR_0119500protein far1-related sequence 11-like isoform-OG0000030--------
GBC12279.1g4040.t1RIR_0119600hypothetical protein-OG0000620--------
GBC12280.1g4041.t1RIR_0119700salt-inducible protein kinase--YPL140C25.272.00E-14"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"AN581526.491.00E-14Aurora protein serine/threonine kinase
GBC12281.1g4042.t1RIR_0119800protein kinase--YPL203W26.859.00E-14cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxiaAN438529.861.00E-13"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12283.1g4044.t1RIR_0120000protein kinase--YHL007C25.366.00E-14"Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family"AN438530.462.00E-15"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12285.1g4046.t1RIR_0120200serine/threonine protein kinase--YNL298W29.818.00E-15"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN438530.21.00E-15"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12287.1g4048.t1RIR_0120400hypothetical protein----------
GBC12288.1g4049.t1RIR_0120500hypothetical protein----------
GBC12290.1g4051.t1RIR_0120700protein kinase--YNL298W33.852.00E-14"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN438528.681.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12292.1g4052.t1RIR_0120800hypothetical protein-OG0000026--------
GBC12293.1g4053.t1RIR_0120900zn-finger domain-containing protein-OG0000026--------
GBC12296.1g4056.t1RIR_0121200hypothetical protein----------
GBC12298.1g4057.t1RIR_0121300putative zinc finger domain-containing protein-OG0000011----AN200933.338.00E-37"Ortholog(s) have role in conidiophore development, conidium formation, hyphal growth"
GBC12299.1g4058.t1RIR_0121400transmembrane protein-OG0002166--------
GBC12300.1g4059.t1RIR_0121500SEL1 protein-OG0000000YDL203C28.168.00E-15Protein that functions in the cell wall integrity pathway; functions upstream of Pkc1p; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondriaAN081026.191.00E-24Protein with a predicted role in ER-associated protein degradation
GBC12301.1g4060.t1RIR_0121600serine/threonine protein kinase--YPL153C28.981.00E-16DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxiaAN438523.928.00E-17"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12302.1JEMT01012489.1_cds_EXX75226.1_4803RIR_0121610JEMT01012489.1_cds_EXX75226.1_4803-OG0002166--------
GBC12303.1Tis13_4297RIR_0121620Tis13_4297----------
GBC12304.1Tis13_10739RIR_0121630Tis13_10739----------
GBC12305.1Tis13_14448RIR_0121640Tis13_14448-OG0000338--------
GBC12306.1g4061.t1RIR_0121700semaphorin-3f-like-OG0000005--------
GBC12307.1g4062.t1RIR_0121800bis(5'-adenosyl)-triphosphatase-like-OG0000005--------
GBC12308.1g4063.t1RIR_0121900serine/threonine protein kinase----------
GBC12309.1g4063.t2RIR_0121900serine/threonine protein kinase------AN597326.672.00E-11Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12310.1g4064.t1RIR_0122000serine/threonine-protein kinase--YAR019C26.453.00E-12Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress----
GBC12311.1g4065.t1RIR_0122100cell wall beta-glucan synthesis family protein-OG0002411--------
GBC12312.1g4066.t1RIR_0122200hypothetical protein----------
GBC12313.1g4067.t1RIR_0122300aaap amino acid permease-OG0003686--------
GBC12314.1g4068.t1RIR_0122400protein kinase-OG0000000YOL016C33.049.00E-13"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN773732.612.00E-11Ortholog(s) have protein serine/threonine kinase activity
GBC12315.1g4068.t2RIR_0122400protein kinase-OG0000000YOL016C33.041.00E-12"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN773732.611.00E-11Ortholog(s) have protein serine/threonine kinase activity
GBC12316.1g4069.t1RIR_0122500hypothetical protein----------
GBC12317.1g4070.t1RIR_0122600protein kinase----------
GBC12318.1g4071.t1RIR_0122700hypothetical protein-OG0000080--------
GBC12319.1g4072.t1RIR_0122800Peptide-methionine-S-oxide reductase-OG0001592YER042W44.197.00E-48Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer diseaseAN1056257.84.00E-72Putative methionine sulfoxide reductase with a predicted role in the reduction of methionine sulfoxide to methionine
GBC12320.1g4073.t1RIR_0122900transmembrane protein----------
GBC12321.1g4074.t1RIR_0123000serine/threonine protein kinase-OG0000000YLR362W24.756.00E-14"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN488729.332.00E-15"Putative mitogen-activated protein kinase kinase kinase (MAPKKK); inviable mutant arrests as branched germlings, remediated by NaCl or sucrose"
GBC12324.1g4075.t1RIR_0123100membrane protein-OG0002166--------
GBC12325.1g4076.t1RIR_0123200aryl-alcohol dehydrogenase aad14-OG0000094YNL331C35.446.00E-60"Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family"AN588736.733.00E-63Predicted GTPase activating protein
GBC12326.1g4077.t1RIR_0123300reverse transcriptase-OG0000001--------
GBC12327.1g4078.t1RIR_0123400protein kinase--YPL203W25.698.00E-13cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxiaAN438529.583.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12330.1g4080.t1RIR_0123600hypothetical protein----------
GBC12331.1g4081.t1RIR_0123700hypothetical protein----------
GBC12332.1g4082.t1RIR_0123800hypothetical protein----------
GBC12333.1g4083.t1RIR_0123900hypothetical protein----------
GBC12334.1g4084.t1RIR_0124000CENP-b protein 1-OG0000010--------
GBC12335.1g4085.t1RIR_0124100hypothetical protein-OG0000010--------
GBC12336.1g4086.t1RIR_0124200hypothetical protein----------
GBC12337.1g4087.t1RIR_0124300hypothetical protein----------
GBC12338.1g4088.t1RIR_0124400hypothetical protein----------
GBC12339.1g4089.t1RIR_0124500hypothetical protein----------
GBC12340.1Tis13_96288RIR_0124510Tis13_96288----------
GBC12341.1g4090.t1RIR_0124600hypothetical protein----------
GBC12342.1g4091.t1RIR_0124700hypothetical protein----------
GBC12343.1g4092.t1RIR_0124800hypothetical protein----------
GBC12344.1g4093.t1RIR_0124900hypothetical protein----------
GBC12345.1g4094.t1RIR_0125000hypothetical protein----------
GBC12346.1g4095.t1RIR_0125100hypothetical protein----------
GBC12347.1g4096.t1RIR_0125200hypothetical protein----------
GBC12348.1g4097.t1RIR_0125300hypothetical protein----------
GBC12349.1g4098.t1RIR_0125400Golgi phosphoprotein 3-OG0001252YDR372C47.463.00E-83"Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33"AN570556.522.00E-99Has domain(s) with predicted phosphatidylinositol-4-phosphate binding activity
GBC12352.1g4099.t1RIR_0125500endopeptidase-OG0000148YPL154C33.741.00E-42"Vacuolar aspartyl protease (proteinase A); required for posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; plays a protective role in acetic acid induced apoptosis; synthesized as a zymogen, self-activates"AN442236.484.00E-54Putative aspartic-type endopeptidase; predicted glycosylphosphatidylinositol (GPI)-anchored protein
GBC12353.1g4100.t1RIR_0125600hypothetical protein----------
GBC12354.1g4101.t1RIR_0125700putative Putative ammonium permease ATO3-OG0000645YNR002C45.616.00E-40"Putative transmembrane protein involved in export of ammonia; ammonia is a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Y. lipolytica Gpr1p; ATO2 has a paralog, ADY2, that arose from the whole genome duplication"AN522635.293.00E-26"Acetate permease, involved in acetate uptake; has similarity to GPR1/FUN34/YaaH family members; transcript induced by ethanol"
GBC12355.1g4102.t1RIR_0125800protein kinase-OG0000248YKL166C25.193.00E-13"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN567426.174.00E-12"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12357.1g4103.t1RIR_0125900ATP-dependent DNA helicase pif1-like-OG0000037YML061C27.872.00E-21"DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells"AN689525.935.00E-22"Has domain(s) with predicted DNA helicase activity and role in DNA repair, telomere maintenance"
GBC12361.1g4107.t1RIR_0126300reverse transcriptase-OG0000001--------
GBC12363.1g4109.t1RIR_0126500serine/threonine protein kinase-OG0000000YLR362W26.832.00E-15"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN488731.334.00E-16"Putative mitogen-activated protein kinase kinase kinase (MAPKKK); inviable mutant arrests as branched germlings, remediated by NaCl or sucrose"
GBC12364.1g4110.t1RIR_0126600btb/poz domain-containing protein 19-OG0000006--------
GBC12365.1JEMT01028581.1_cds_EXX54209.1_25820RIR_0126610JEMT01028581.1_cds_EXX54209.1_25820-OG0000007--------
GBC12366.1g4111.t1RIR_0126700"protein kinase, putative"--YKL166C28.97.00E-14"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN438531.161.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12367.1g4112.t1RIR_0126800protein kinase--YOR231W31.475.00E-14"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN597328.937.00E-14Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC12368.1g4113.t1RIR_0126900mitogen-activated protein kinase kinase kinase-OG0000041YAR019C252.00E-12Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN567428.092.00E-14"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12371.1g4114.t1RIR_0127000serine-enriched protein-OG0000006--------
GBC12372.1g4115.t1RIR_0127100btb/poz domain-containing protein 9-like-OG0000006--------
GBC12373.1g4116.t1RIR_0127200protein kinase-OG0000000YKL166C26.941.00E-13"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN438531.472.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12374.1g4117.t1RIR_0127300SEL1 protein-OG0000000YBL061C31.583.00E-20"Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication"AN081026.091.00E-30Protein with a predicted role in ER-associated protein degradation
GBC12376.1g4118.t2RIR_0127400putative serine/threonine-protein--YMR001C29.363.00E-14Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN950431.33.00E-12Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12377.1g4118.t1RIR_0127400putative serine/threonine-protein--YOL016C29.075.00E-15"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN950431.066.00E-13Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12378.1g4119.t1RIR_0127500Sentrin-specific protease 1-OG0000270YPL020C28.182.00E-12Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions----
GBC12379.1g4120.t1RIR_0127600"protein kinase, putative"--YPL209C34.041.00E-12"Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest"AN438529.554.00E-13"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12380.1Tis13_23997RIR_0127610Tis13_23997----------
GBC12381.1g4121.t1RIR_0127700serine/threonine-protein kinase--YKL166C26.644.00E-11"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN241232.733.00E-11Calcium/calmodulin-dependent protein kinase A; essential for growth and nuclear division; expression downregulated by farnesol; transcript upregulated by camptothecin; mutants have a moderate growth defect and increased pigment production
GBC12382.1g4122.t1RIR_0127800kelch-like protein 17-OG0000006--------
GBC12383.1g4123.t1RIR_0127900"protein kinase, putative"-OG0000000YMR001C29.895.00E-13Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate----
GBC12385.1g4125.t1RIR_0128100hypothetical protein----------
GBC12386.1g4126.t1RIR_0128200hypothetical protein----------
GBC12387.1g4127.t1RIR_0128300hypothetical protein----------
GBC12388.1g4128.t2RIR_0128400hypothetical protein----------
GBC12389.1g4128.t1RIR_0128400hypothetical protein----------
GBC12390.1g4129.t2RIR_0128500serine/threonine protein kinase-OG0000000YDR523C27.764.00E-19Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN1015326.791.00E-20Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC12391.1g4129.t1RIR_0128500serine/threonine protein kinase-OG0000000--------
GBC12393.1g4131.t1RIR_0128700serine/threonine kinase-OG0000000YFR014C28.12.00E-14"Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication"AN567426.972.00E-12"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12395.1g4133.t3RIR_0128900hypothetical protein----------
GBC12396.1g4133.t2RIR_0128900hypothetical protein----------
GBC12397.1g4133.t1RIR_0128900hypothetical protein----------
GBC12398.1g4134.t3RIR_0129000hypothetical protein----------
GBC12399.1g4134.t4RIR_0129000hypothetical protein----------
GBC12400.1g4134.t2RIR_0129000hypothetical protein----------
GBC12401.1g4134.t1RIR_0129000hypothetical protein----------
GBC12402.1g4134.t5RIR_0129000hypothetical protein----------
GBC12403.1g4135.t1RIR_0129100hsp70 family protein-OG0000043----AN086625.221.00E-28"Ortholog of A. nidulans FGSC A4 : AN3519, AN2646, AN0587, AN7370 and A. fumigatus Af293 : Afu1g15200, Afu3g03790, Afu4g14040, Afu5g06900, Afu7g08575"
GBC12404.1g4136.t1RIR_0129200hsp70 family protein----------
GBC12405.1g4137.t1RIR_0129300hsp70 family protein-OG0000043----AN058729.666.00E-23Putative Hsp70 family chaperone; transcript is induced by nitrate
GBC12407.1g4138.t1RIR_0129400serine/threonine protein kinase-OG0000078YMR104C27.091.00E-14"Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication"AN438526.422.00E-17"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12410.1g4141.t1RIR_0129700salt-inducible protein kinase--YMR001C28.892.00E-15Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN206733.792.00E-13Predicted PAK (p21-activated kinase) family protein; similar to Saccharomyces cerevisiae Ste20p; mutants have increased pigment production
GBC12411.1g4142.t1RIR_0129800protein kinase-OG0000248YAR019C27.472.00E-12Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress----
GBC12412.1g4143.t1RIR_0129900umta methyltransferase family protein-OG0000025----AN587428.032.00E-16Putative LaeA-like methyltransferase
GBC12413.1g4144.t1RIR_0130000salt-inducible protein kinase-OG0000248YOR231W27.066.00E-14"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN950432.373.00E-12Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12414.1g4145.t1RIR_0130100serine-threonine protein kinase-OG0000000YAR019C29.233.00E-14Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN950432.097.00E-12Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC12415.1g4146.t1RIR_0130200ATP-dependent DNA helicase PIF1-OG0000037YML061C506.00E-24"DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells"AN527825.545.00E-18"Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance"
GBC12416.1g4147.t1RIR_0130300zinc finger bed domain-containing protein-OG0000008----AN1107435.864.00E-29Predicted hAT transposon-related ORF
GBC12419.1g4150.t1RIR_0130600transcriptional factor b3-OG0000062----AN527835.840"Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance"
GBC12420.1g4151.t1RIR_0130700probable carboxypeptidase x1 isoform x2----------
GBC12421.1g4152.t1RIR_0130800hypothetical protein----------
GBC12425.1g4156.t1RIR_0131200"protein kinase, putative"-OG0000248YOL113W32.11.00E-16"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN567430.22.00E-17"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12426.1g4157.t1RIR_0131300GTPase imap family member 8-like-OG0004813--------
GBC12427.1g4158.t1RIR_0131400sonic hedgehog protein a isoform x1-OG0000154--------
GBC12428.1g4159.t1RIR_0131500GTPase imap family member 7-like-OG0000154--------
GBC12429.1g4160.t1RIR_0131600GTPase imap family member 7-like-OG0000154--------
GBC12430.1JEMT01026557.1_cds_EXX58989.1_21046RIR_0131610JEMT01026557.1_cds_EXX58989.1_21046----------
GBC12432.1g4162.t1RIR_0131800retroviral-like aspartic protease 1-OG0000066--------
GBC12433.1g4163.t1RIR_0131900retrotransposable element-OG0000004YIL082W-A38.121.00E-70"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547034.83.00E-65Predicted gypsy transposon-related ORF
GBC12434.1g4164.t1RIR_0132000retrotransposable element-OG0000004YGR109W-B24.338.00E-18"Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN1064927.477.00E-23"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC12436.1g4165.t1RIR_0132100GTPase imap family member 7-like-OG0004813--------
GBC12437.1g4166.t1RIR_0132200GTPase imap family member 4-like-OG0000154--------
GBC12438.1g4167.t1RIR_0132300GTPase imap family member 4-OG0000154--------
GBC12439.1JEMT01028253.1_cds_EXX55268.1_24765RIR_0132310JEMT01028253.1_cds_EXX55268.1_24765----------
GBC12440.1g4168.t1RIR_0132400hypothetical protein----------
GBC12441.1JEMT01028253.1_cds_EXX55269.1_24766RIR_0132410JEMT01028253.1_cds_EXX55269.1_24766----------
GBC12442.1g4169.t1RIR_0132500"protein kinase, putative"-OG0000000YOR231W30.775.00E-13"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN438527.782.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12443.1g4170.t1RIR_0132600protein kinase--YMR001C29.911.00E-13Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN438530.779.00E-13"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12444.1g4171.t1RIR_0132700putative Sacsin-OG0000482--------
GBC12446.1g4173.t1RIR_0132900hypothetical protein----------
GBC12447.1g4174.t1RIR_0133000salt-inducible protein kinase-OG0000000YNL298W32.723.00E-15"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN567426.99.00E-13"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12448.1g4174.t2RIR_0133000salt-inducible protein kinase-OG0000000YNL298W32.723.00E-15"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN567426.99.00E-13"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12449.1g4175.t1RIR_0133100serine/threonine protein kinase-OG0000038YHR102W25.831.00E-16"Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"AN1103226.251.00E-15"Protein kinase; mutants are sensitive to NaCl, have a strong growth defect and display defects in septation and conidiation"
GBC12452.1g4178.t1RIR_0133400"protein kinase, putative"-OG0000000YAR019C26.96.00E-14Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN438530.998.00E-14"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12453.1g4179.t1RIR_0133500protein kinase-OG0000000YMR001C26.153.00E-12Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN438531.032.00E-13"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12455.1g4181.t1RIR_0133700hypothetical protein-OG0004555--------
GBC12457.1g4183.t1RIR_0133900protein kinase--YPL140C27.885.00E-12"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"AN438531.652.00E-11"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12458.1g4184.t1RIR_0134000proteoglycan 4----------
GBC12461.1g4187.t1RIR_0134300serine/threonine protein kinase--YPL153C26.925.00E-15DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxiaAN306532.477.00E-15"Essential Ca2+/calmodulin-dependent protein kinase, required for nuclear division; required for normal timing of NimX activation at G1/S transition"
GBC12462.1g4188.t1RIR_0134400serine/threonine protein kinase-OG0000038YHR102W25.372.00E-13"Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"AN1015324.253.00E-13Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC12463.1g4189.t1RIR_0134500wd40 repeat-containing protein--YAR019C29.552.00E-14Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress----
GBC12464.1g4190.t1RIR_0134600umta methyltransferase family protein-OG0000025--------
GBC12465.1g4191.t1RIR_0134700protein kinase-OG0000248YAR019C26.498.00E-13Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN773731.251.00E-12Ortholog(s) have protein serine/threonine kinase activity
GBC12466.1g4192.t1RIR_0134800protein kinase--YKL166C30.893.00E-13"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN630526.346.00E-11cAMP-dependent protein kinase catalytic subunit; cAMP signaling during conidial germination; overlapping functions with SchA; induced by osmotic stress; mutant growth defect remediated by sucrose and NaCl; reduced growth on AVICEL medium
GBC12468.1g4193.t1RIR_0134900kelch-like protein 17-OG0000006--------
GBC12469.1g4194.t1RIR_0135000zinc finger mym-type protein 2-like----------
GBC12470.1g4195.t1RIR_0135100hypothetical protein----------
GBC12471.1g4196.t1RIR_0135200mitogen-activated protein kinase kinase kinase----------
GBC12472.1g4197.t1RIR_0135300tkl/lisk/lisk-dd1 protein kinase----------
GBC12473.1JEMT01012764.1_cds_EXX74653.1_5375RIR_0135310JEMT01012764.1_cds_EXX74653.1_5375----------
GBC12474.1g4198.t1RIR_0135400ATP-dependent DNA helicase pif1-like-OG0000037--------
GBC12475.1g4199.t1RIR_0135500hypothetical protein----------
GBC12476.1g4200.t1RIR_0135600serine-threonine protein kinase-OG0000248YAR019C26.23.00E-12Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN1015327.929.00E-11Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC12477.1g4201.t1RIR_0135700protein kinase-OG0000000YMR001C25.52.00E-14Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN438531.858.00E-14"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12479.1g4202.t1RIR_0135800serine-threonine protein kinase-OG0000248YKL166C37.612.00E-11"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"----
GBC12481.1g4203.t1RIR_0135900hypothetical protein-OG0000464--------
GBC12482.1g4204.t1RIR_0136000Srm1p-OG0000657YGL097W28.643.00E-46"Nucleotide exchange factor for Gsp1p; localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p"AN697831.594.00E-41Putative nucleotide exchange factor involved in nucleocytoplasmic trafficking of macromolecules
GBC12484.1g4206.t1RIR_0136200"ER organization and biogenesis-related protein,"-OG0002494YDR320C28.274.00E-29Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesiclesAN879832.262.00E-44"Ortholog of A. fumigatus Af293 : Afu5g09630, A. niger CBS 513.88 : An07g03250, A. oryzae RIB40 : AO090020000592, Aspergillus wentii : Aspwe1_0023820 and Aspergillus sydowii : Aspsy1_0159494"
GBC12485.1g4207.t1RIR_0136300g-patch domain-containing protein-OG0000917----AN356722.481.00E-13"Ortholog of Aspergillus wentii : Aspwe1_0105538, Aspergillus versicolor : Aspve1_0195944 and Aspergillus sydowii : Aspsy1_0057674"
GBC12486.1g4208.t1RIR_0136400clathrin-coated vesicle protein-OG0002332YJL207C25.851.00E-27AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential geneAN659831.70"Ortholog(s) have role in endocytosis and endocytic vesicle, nucleus localization"
GBC12487.1g4209.t1RIR_0136500hypothetical protein----------
GBC12488.1g4210.t1RIR_0136600hypothetical protein----------
GBC12489.1g4211.t1RIR_0136700hypothetical protein----------
GBC12493.1g4215.t1RIR_0137100DNA polymerase-OG0000287--------
GBC12494.1g4216.t1RIR_0137200hypothetical protein-OG0000004--------
GBC12497.1g4219.t1RIR_0137500hypothetical protein-OG0000366--------
GBC12500.1g4222.t1RIR_0137800DNA polymerase epsilon catalytic subunit a-OG0000463----AN1075526.051.00E-10"Ortholog(s) have DNA replication origin binding, DNA-directed DNA polymerase activity, chromatin binding, single-stranded DNA binding activity"
GBC12502.1g4224.t1RIR_0138000hypothetical protein----------
GBC12504.1g4226.t1RIR_0138200uvr/rep helicase----------
GBC12505.1g4227.t1RIR_0138300hypothetical protein----------
GBC12506.1g4228.t1RIR_0138400hypothetical protein----------
GBC12507.1Tis13_105280RIR_0138410Tis13_105280----------
GBC12508.1g4229.t1RIR_0138500hypothetical protein-OG0000069--------
GBC12509.1g4230.t1RIR_0138600hypothetical protein----------
GBC12510.1g4231.t1RIR_0138700hypothetical protein----------
GBC12511.1g4232.t1RIR_0138800hypothetical protein----------
GBC12512.1g4233.t1RIR_0138900hypothetical protein-OG0000080--------
GBC12513.1g4234.t1RIR_0139000hypothetical protein----------
GBC12514.1g4235.t1RIR_0139100hypothetical protein----------
GBC12515.1g4236.t1RIR_0139200hypothetical protein-OG0000047--------
GBC12518.1g4239.t1RIR_0139500highly derived d5-like helicase-primase----------
GBC12519.1g4239.t2RIR_0139500highly derived d5-like helicase-primase----------
GBC12520.1g4240.t1RIR_0139600serine/threonine protein kinase-OG0000001YJL095W27.671.00E-12MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinaseAN1015322.996.00E-11Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC12522.1g4242.t1RIR_0139800hypothetical protein----------
GBC12523.1g4243.t1RIR_0139900hypothetical protein----------
GBC12524.1g4244.t1RIR_0140000hypothetical protein----------
GBC12525.1g4245.t1RIR_0140100serine/threonine/tyrosine protein kinase rad53----------
GBC12526.1g4246.t1RIR_0140200Galactokinase-OG0002442YDR009W37.058.00E-108"Transcriptional regulator; involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity; GAL3 has a paralog, GAL1, that arose from the whole genome duplication"AN495737.142.00E-115Putative galactokinase with a predicted role in galactose and galactitol metabolism
GBC12527.1g4247.t2RIR_0140300translation regulator-OG0000110--------
GBC12528.1g4247.t1RIR_0140300translation regulator-OG0000110--------
GBC12529.1g4248.t1RIR_0140400hypothetical protein----------
GBC12530.1g4249.t1RIR_0140500hypothetical protein----------
GBC12531.1g4250.t1RIR_0140600Phospholipase D1/2-OG0000377YKR031C57.147.00E-125"Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with ""foot domain"" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions"AN671239.441.00E-166Putative phospholipase D; expression upregulated after exposure to farnesol
GBC12532.1g4251.t1RIR_0140700hypothetical protein----------
GBC12533.1g4252.t1RIR_0140800umta methyltransferase family protein-OG0000025----AN216531.581.00E-13Putative LaeA-like methyltransferase
GBC12534.1g4253.t1RIR_0140900Peroxisomal membrane protein 4-OG0003799----AN148348.953.00E-53"Ortholog of A. fumigatus Af293 : Afu8g04780, A. niger CBS 513.88 : An16g08040, A. oryzae RIB40 : AO090005000669, Aspergillus wentii : Aspwe1_0643990 and Aspergillus sydowii : Aspsy1_0055812"
GBC12535.1g4254.t1RIR_0141000mitochondrial ribosomal protein subunit l11-OG0002428--------
GBC12536.1g4255.t1RIR_0141100duf423 protein-OG0004101--------
GBC12537.1g4255.t2RIR_0141100duf423 protein-OG0004101--------
GBC12538.1g4256.t1RIR_0141200DnaJ homolog subfamily B member 4-OG0000067YNL007C35.021.00E-29Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1AN223837.416.00E-39Has domain(s) with predicted unfolded protein binding activity and role in protein folding
GBC12539.1Tis13_335549RIR_0141210Tis13_335549----------
GBC12540.1g4257.t2RIR_0141300hypothetical protein----------
GBC12541.1g4257.t1RIR_0141300hypothetical protein----------
GBC12542.1g4258.t1RIR_0141400hypothetical protein-OG0003626YNL107W39.626.00E-17Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes; may function to antagonize silencing near telomeres; interacts directly with Swc4p; has homology to human leukemogenic protein AF9; contains a YEATS domainAN1018147.172.00E-11"Ortholog of A. fumigatus Af293 : Afu1g09530, A. niger CBS 513.88 : An08g01090, A. oryzae RIB40 : AO090012000919, Neosartorya fischeri NRRL 181 : NFIA_016080 and Aspergillus wentii : Aspwe1_0036341"
GBC12543.1g4259.t1RIR_0141500hypothetical protein----------
GBC12544.1g4260.t1RIR_0141600hypothetical protein----------
GBC12549.1g4262.t1RIR_0141800transposase domain-containing protein-OG0000002--------
GBC12550.1g4263.t1RIR_0141900hypothetical protein-OG0000002--------
GBC12552.1g4265.t1RIR_0142100hypothetical protein-OG0000002--------
GBC12553.1g4266.t1RIR_0142200hypothetical protein-OG0000002--------
GBC12557.1JEMT01016063.1_cds_EXX71618.1_8411RIR_0142510JEMT01016063.1_cds_EXX71618.1_8411----------
GBC12559.1g4271.t1RIR_0142700CENP-b protein 1-OG0000010YDR081C21.131.00E-12Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditionsAN871732.042.00E-48"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC12561.1g4273.t1RIR_0142900hypothetical protein-OG0001124--------
GBC12563.1JEMT01018155.1_cds_EXX66941.1_13086RIR_0143010JEMT01018155.1_cds_EXX66941.1_13086----------
GBC12565.1g4275.t1RIR_0143100transposase domain-containing protein-OG0000002--------
GBC12567.1g4277.t1RIR_0143300gastrula zinc finger protein xlcgf46.1----------
GBC12568.1g4278.t2RIR_0143400zinc finger bed domain-containing protein-OG0000008--------
GBC12569.1g4278.t1RIR_0143400zinc finger bed domain-containing protein-OG0000008--------