GBC49257.1

Protein

Length

718 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 96
BRCT domain (IPR001357)
202 - 330
WGR domain (IPR008893)
487 - 718
Poly(ADP-ribose) polymerase, catalytic domain (IPR012317)
Domain
364 - 494
Poly(ADP-ribose) polymerase, regulatory domain (IPR004102)

1 100 200 300 400 500 600 718

Detailed signature matches

IPR001357

BRCT domain
1. SM00292 (BRCT_7)
  
  2 - 85
  
  SMART
  SM00292 (BRCT_7)
2. PS50172 (BRCT)
  
  1 - 95
  
  PROSITE profiles
  PS50172 (BRCT)
3. SSF52113 (BRCT domain)
  
  3 - 96
  
  SUPERFAMILY
  SSF52113 (BRCT domain)
4. cd00027 (BRCT)
  
  7 - 83
  
  CDD
  cd00027 (BRCT)
5. PF00533 (BRCT)
  
  3 - 82
  
  Pfam
  PF00533 (BRCT)
IPR008893

WGR domain
1. SSF142921 (WGR doma...)
  
  202 - 330
  
  SUPERFAMILY
  SSF142921 (WGR domain-like)
2. PF05406 (WGR)
  
  235 - 311
  
  Pfam
  PF05406 (WGR)
3. SM00773 (WGR_cls)
  
  235 - 320
  
  SMART
  SM00773 (WGR_cls)
IPR004102

Poly(ADP-ribose) polymerase, regulatory domain
1. PF02877 (PARP_reg)
  
  365 - 493
  
  Pfam
  PF02877 (PARP_reg)
2. SSF47587 (Domain of...)
  
  364 - 494
  
  SUPERFAMILY
  SSF47587 (Domain of poly(ADP-ribose) polymerase)
3. PS51060 (PARP_ALPHA_HD)
  
  364 - 480
  
  PROSITE profiles
  PS51060 (PARP_ALPHA_HD)
IPR012317

Poly(ADP-ribose) polymerase, catalytic domain
1. PF00644 (PARP)
  
  500 - 711
  
  Pfam
  PF00644 (PARP)
2. PS51059 (PARP_CATAL...)
  
  487 - 718
  
  PROSITE profiles
  PS51059 (PARP_CATALYTIC)

no IPR

Unintegrated signatures

Coil

338 - 358

COILS
Coil (Coil)
SSF56399 (ADP-ribos...)

501 - 715

SUPERFAMILY
SSF56399 (ADP-ribosylation)
cd01437 (parp_like)

364 - 710

CDD
cd01437 (parp_like)
mobidb-lite (disord...)

92 - 164

MobiDB Lite
mobidb-lite (disorder_prediction)

334 - 366

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Dimer interface cd...

22A

Dimer interface
22A, 26S, 29R, 32G, 34Q
CDD
cd00027 (BRCT)

26S

Dimer interface
22A, 26S, 29R, 32G, 34Q
CDD
cd00027 (BRCT)

29R

Dimer interface
22A, 26S, 29R, 32G, 34Q
CDD
cd00027 (BRCT)

32G

Dimer interface
22A, 26S, 29R, 32G, 34Q
CDD
cd00027 (BRCT)

34Q

Dimer interface
22A, 26S, 29R, 32G, 34Q
CDD
cd00027 (BRCT)
BRCT sequence moti...

77W

BRCT sequence motif
77W, 81S
CDD
cd00027 (BRCT)

81S

BRCT sequence motif
77W, 81S
CDD
cd00027 (BRCT)
parp regulatory do...

364E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

365S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

366T

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

367L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

368H

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

369P

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

370K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

371V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

372Q

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

373D

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

374I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

375V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

376N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

377M

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

378I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

379F

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

380D

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

381V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

382N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

383Q

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

384W

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

385K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

386E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

387A

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

388M

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

389K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

390E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

391F

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

392E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

393Y

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

394D

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

395S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

396V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

397K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

398L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

399P

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

400L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

401G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

402K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

403I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

404G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

405K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

406S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

407T

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

408I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

409N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

410Q

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

411G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

412Y

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

413G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

414I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

415L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

416K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

417R

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

418I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

419E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

420S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

421V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

422L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

423M

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

424G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

425K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

426S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

428E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

429N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

430L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

431E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

432T

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

433L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

434S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

435N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

436N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

437F

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

438Y

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

439T

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

440V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

441I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

442P

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

443H

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

444Y

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

445F

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

446G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

447M

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

448R

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

449K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

450P

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

451L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

452I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

453I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

458L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

459L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

460K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

461A

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

462K

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

463L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

464E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

465M

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

466V

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

467E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

468T

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

469L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

470G

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

471E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

472I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

473E

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

474I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

475A

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

476N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

477S

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

478L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

479N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

480I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

486I

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

487N

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

488P

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

489L

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

490D

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

491A

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

492H

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)

493Y

parp regulatory domain
364E, 365S, 366T, 367L, 368H, 369P, 370K, 371V, 372Q, 373D, 374I, 375V, 376N, 377M, 378I, 379F, 380D, 381V, 382N, 383Q, 384W, 385K, 386E, 387A, 388M, 389K, 390E, 391F, 392E, 393Y, 394D, 395S, 396V, 397K, 398L, 399P, 400L, 401G, 402K, 403I, 404G, 405K, 406S, 407T, 408I, 409N, 410Q, 411G, 412Y, 413G, 414I, 415L, 416K, 417R, 418I, 419E, 420S, 421V, 422L, 423M, 424G, 425K, 426S, 428E, 429N, 430L, 431E, 432T, 433L, 434S, 435N, 436N, 437F, 438Y, 439T, 440V, 441I, 442P, 443H, 444Y, 445F, 446G, 447M, 448R, 449K, 450P, 451L, 452I, 453I, 458L, 459L, 460K, 461A, 462K, 463L, 464E, 465M, 466V, 467E, 468T, 469L, 470G, 471E, 472I, 473E, 474I, 475A, 476N, 477S, 478L, 479N, 480I, 486I, 487N, 488P, 489L, 490D, 491A, 492H, 493Y
CDD
cd01437 (parp_like)
Inhibitor contact ...

467E

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

470G

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

471E

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

562H

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

563G

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

568N

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

578R

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

579I

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

580A

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

596Y

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

597F

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

598A

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

604S

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

607Y

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

692E

Inhibitor contact residues
467E, 470G, 471E, 562H, 563G, 568N, 578R, 579I, 580A, 596Y, 597F, 598A, 604S, 607Y, 692E
CDD
cd01437 (parp_like)
nad+ contact resid...

467E

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

471E

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

562H

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

563G

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

564S

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

572I

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

576G

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

577L

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

578R

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

596Y

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

604S

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

607Y

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

692E

nad+ contact residues
467E, 471E, 562H, 563G, 564S, 572I, 576G, 577L, 578R, 596Y, 604S, 607Y, 692E
CDD
cd01437 (parp_like)

GO term prediction

Biological Process

GO:0006471 protein ADP-ribosylation

Molecular Function

GO:0003950 NAD+ ADP-ribosyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC49257.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component