GBC48851.1

Protein

Length

743 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
7 - 217
von Willebrand factor, type A (IPR002035)
228 - 424
Ku70/Ku80 beta-barrel domain (IPR006164)
569 - 715
Ku, C-terminal (IPR014893)
Domain
206 - 532
SPOC-like, C-terminal domain (IPR016194)

1 100 200 300 400 500 600 743

Detailed signature matches

IPR002035

von Willebrand factor, type A
1. SSF53300 (vWA-like)
  
  7 - 217
  
  SUPERFAMILY
  SSF53300 (vWA-like)
IPR016194

SPOC-like, C-terminal domain
1. SSF100939 (SPOC dom...)
  
  206 - 532
  
  SUPERFAMILY
  SSF100939 (SPOC domain-like)
IPR006164

Ku70/Ku80 beta-barrel domain
1. PF02735 (Ku)
  
  228 - 424
  
  Pfam
  PF02735 (Ku)
2. SM00559 (ku_4)
  
  282 - 419
  
  SMART
  SM00559 (ku_4)
IPR014893

Ku, C-terminal
1. PF08785 (Ku_PK_bind)
  
  597 - 714
  
  Pfam
  PF08785 (Ku_PK_bind)
2. SSF101420 (C-termin...)
  
  569 - 715
  
  SUPERFAMILY
  SSF101420 (C-terminal domain of Ku80)

no IPR

Unintegrated signatures

cd00873 (KU80)

207 - 532

CDD
cd00873 (KU80)
mobidb-lite (disord...)

560 - 584

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterodimer interf...

218D

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

228L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

235A

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

237T

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

238M

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

239K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

240A

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

244S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

246K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

247K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

249S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

258I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

264E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

265V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

266S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

267H

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

268S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

269R

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

270T

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

271Y

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

285V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

289E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

291D

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

292K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

293A

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

295A

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

296L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

297G

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

298K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

299T

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

310I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

312S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

322I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

323S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

324F

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

325I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

329E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

332R

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

333E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

335V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

336L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

339V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

348E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

350V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

353Q

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

356S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

358F

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

367S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

372R

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

380S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

391K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

395E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

402I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

405K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

406E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

407D

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

409R

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

412T

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

413F

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

414P

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

415S

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

443G

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

447E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

449L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

451L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

466L

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

469K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

471C

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

472Y

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

473N

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

478M

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

483V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

486K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

487A

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

502K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

505T

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

506R

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

507M

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

519V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

528I

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

529K

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

530E

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)

531V

heterodimer interface
218D, 228L, 235A, 237T, 238M, 239K, 240A, 244S, 246K, 247K, 249S, 258I, 264E, 265V, 266S, 267H, 268S, 269R, 270T, 271Y, 285V, 289E, 291D, 292K, 293A, 295A, 296L, 297G, 298K, 299T, 310I, 312S, 322I, 323S, 324F, 325I, 329E, 332R, 333E, 335V, 336L, 339V, 348E, 350V, 353Q, 356S, 358F, 367S, 372R, 380S, 391K, 395E, 402I, 405K, 406E, 407D, 409R, 412T, 413F, 414P, 415S, 443G, 447E, 449L, 451L, 466L, 469K, 471C, 472Y, 473N, 478M, 483V, 486K, 487A, 502K, 505T, 506R, 507M, 519V, 528I, 529K, 530E, 531V
CDD
cd00873 (KU80)
DNA binding site c...

235A

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

245F

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

246K

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

267H

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

305K

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

317P

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

338N

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

375K

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

376K

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

377P

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

378L

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

379E

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

380S

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

409R

DNA binding site
235A, 245F, 246K, 267H, 305K, 317P, 338N, 375K, 376K, 377P, 378L, 379E, 380S, 409R
CDD
cd00873 (KU80)

GO term prediction

Biological Process

GO:0006303 double-strand break repair via nonhomologous end joining

Molecular Function

GO:0003677 DNA binding
GO:0016817 hydrolase activity, acting on acid anhydrides

Cellular Component