Protein

GBC44343.1

Length
862 amino acids

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 862

Detailed signature matches

  1. Family IPR005671
    2-isopropylmalate synthase, bacterial-type
    1. TIGR00973
    2. MF_01025 (LeuA_type1)
  2. Domain IPR006068
    Cation-transporting P-type ATPase, C-terminal
    1. PF00689 (Cation_ATP...)
  3. Domain IPR000891
    Pyruvate carboxyltransferase
    1. PS50991 (PYR_CT)
    2. PF00682 (HMGL-like)
  4. Domain IPR013709
    2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
    1. SM00917 (LeuA_dimer_2)
    2. SSF110921 (2-isopro...)
    3. PF08502 (LeuA_dimer)
  5. SITE IPR002034
    Alpha-isopropylmalate/homocitrate synthase, conserved site
    1. PS00816 (AIPM_HOMOC...)
    2. PS00815 (AIPM_HOMOC...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51569 (Aldolase)
  2. SSF81665 (Calcium A...)
  3. cd07940 (DRE_TIM_IPMS)
  4. mobidb-lite (disord...)

Residue annotation

  1. catalytic residues...
  2. active site cd07940
  3. metal binding site...

GO term prediction

Biological Process

GO:0009098 leucine biosynthetic process
GO:0019752 carboxylic acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0003852 2-isopropylmalate synthase activity
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Cellular Component

None predicted.