GBC43579.1

Protein

Length

892 amino acids

Protein family membership

Histidine biosynthesis trifunctional-protein (IPR016298)

Phosphoribosyl-ATP pyrophosphohydrolase-like (IPR021130)
- Phosphoribosyl-ATP pyrophosphohydrolase (IPR008179)

Histidinol dehydrogenase (IPR012131)

Domains and repeats

Domain
247 - 317
Phosphoribosyl-AMP cyclohydrolase domain (IPR002496)
483 - 887
Aldehyde/histidinol dehydrogenase (IPR016161)

1 100 200 300 400 500 600 700 800 892

Detailed signature matches

IPR016298

Histidine biosynthesis trifunctional-protein
1. PIRSF001257 (HIS4)
  
  14 - 892
  
  PIRSF
  PIRSF001257 (HIS4)
IPR021130

Phosphoribosyl-ATP pyrophosphohydrolase-like
1. PF01503 (PRA-PH)
  
  324 - 405
  
  Pfam
  PF01503 (PRA-PH)
IPR008179

Phosphoribosyl-ATP pyrophosphohydrolase
1. TIGR03188
  
  323 - 402
  
  TIGRFAMs
  TIGR03188 (TIGR03188)
IPR012131

Histidinol dehydrogenase
1. cd06572 (Histidinol_dh)
  
  485 - 879
  
  CDD
  cd06572 (Histidinol_dh)
2. PR00083 (HOLDHDRGNASE)
  
  625 - 651
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  489 - 513
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  688 - 709
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  710 - 729
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  590 - 616
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  655 - 680
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  821 - 839
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
  
  780 - 805
  
  PRINTS
  PR00083 (HOLDHDRGNASE)
3. PF00815 (Histidinol_dh)
  
  476 - 887
  
  Pfam
  PF00815 (Histidinol_dh)
4. MF_01024 (HisD)
  
  461 - 887
  
  HAMAP
  MF_01024 (HisD)
5. TIGR00069
  
  489 - 886
  
  TIGRFAMs
  TIGR00069 (TIGR00069)
IPR002496

Phosphoribosyl-AMP cyclohydrolase domain
1. PF01502 (PRA-CH)
  
  247 - 317
  
  Pfam
  PF01502 (PRA-CH)
2. PD002610
  
  267 - 317
  
  ProDom
  PD002610 (PD002610)
IPR016161

Aldehyde/histidinol dehydrogenase
1. SSF53720 (ALDH-like)
  
  483 - 887
  
  SUPERFAMILY
  SSF53720 (ALDH-like)
IPR001692

Histidinol dehydrogenase, conserved site
1. PS00611 (HISOL_DEHY...)
  
  688 - 720
  
  PROSITE patterns
  PS00611 (HISOL_DEHYDROGENASE)

no IPR

Unintegrated signatures

Coil

873 - 892

COILS
Coil (Coil)
SSF101386 (all-alph...)

323 - 405

SUPERFAMILY
SSF101386 (all-alpha NTP pyrophosphatases)
SSF141734 (HisI-like)

220 - 330

SUPERFAMILY
SSF141734 (HisI-like)
cd11546 (NTP-PPase_...)

322 - 405

CDD
cd11546 (NTP-PPase_His4)
mobidb-lite (disord...)

430 - 451

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

metal binding site...

360E

metal binding site
360E, 363E, 376E, 379D
CDD
cd11546 (NTP-PPase_His4)

363E

metal binding site
360E, 363E, 376E, 379D
CDD
cd11546 (NTP-PPase_His4)

376E

metal binding site
360E, 363E, 376E, 379D
CDD
cd11546 (NTP-PPase_His4)

379D

metal binding site
360E, 363E, 376E, 379D
CDD
cd11546 (NTP-PPase_His4)
NAD binding site c...

511F

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

583Y

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

585P

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

586G

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

594T

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

615P

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

642G

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

643G

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

645Q

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

666P

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

667G

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

668N

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

670Y

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

671V

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)

720H

NAD binding site
511F, 583Y, 585P, 586G, 594T, 615P, 642G, 643G, 645Q, 666P, 667G, 668N, 670Y, 671V, 720H
CDD
cd06572 (Histidinol_dh)
dimerization inter...

535S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

536T

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

539A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

540I

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

542R

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

545D

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

546N

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

549K

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

550F

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

553A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

554Q

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

562V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

564T

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

568V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

569V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

570C

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

571S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

572R

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

575R

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

577I

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

589A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

590I

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

591L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

592P

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

593S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

661D

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

676M

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

680N

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

708A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

709Y

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

712S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

713D

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

715L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

716S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

717Q

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

719E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

720H

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

791H

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

796E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

799L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

800E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

802I

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

803E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

804N

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

805A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

806G

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

807S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

808V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

809F

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

810V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

812P

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

814S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

815P

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

817S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

818C

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

819G

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

820D

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

821Y

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

823S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

825T

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

835A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

836R

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

838Y

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

839S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

840G

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

841V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

842N

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

844L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

845T

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

848K

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

849H

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

850I

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

851T

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

852S

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

853Q

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

854Q

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

855L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

870L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

871A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

873V

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

874E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

875E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

876L

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

877E

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

878A

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)

879H

dimerization interface
535S, 536T, 539A, 540I, 542R, 545D, 546N, 549K, 550F, 553A, 554Q, 562V, 564T, 568V, 569V, 570C, 571S, 572R, 575R, 577I, 589A, 590I, 591L, 592P, 593S, 661D, 676M, 680N, 708A, 709Y, 712S, 713D, 715L, 716S, 717Q, 719E, 720H, 791H, 796E, 799L, 800E, 802I, 803E, 804N, 805A, 806G, 807S, 808V, 809F, 810V, 812P, 814S, 815P, 817S, 818C, 819G, 820D, 821Y, 823S, 825T, 835A, 836R, 838Y, 839S, 840G, 841V, 842N, 844L, 845T, 848K, 849H, 850I, 851T, 852S, 853Q, 854Q, 855L, 870L, 871A, 873V, 874E, 875E, 876L, 877E, 878A, 879H
CDD
cd06572 (Histidinol_dh)
product binding si...

591L

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

593S

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

695S

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

720H

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

786E

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

787H

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

816E

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

820D

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

821Y

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

827H

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

874E

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

876L

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

879H

product binding site
591L, 593S, 695S, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)
substrate binding ...

593S

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

695S

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

717Q

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

720H

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

786E

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

787H

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

816E

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

820D

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

821Y

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

827H

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

874E

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

876L

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)

879H

substrate binding site
593S, 695S, 717Q, 720H, 786E, 787H, 816E, 820D, 821Y, 827H, 874E, 876L, 879H
CDD
cd06572 (Histidinol_dh)
zinc binding site ...

717Q

zinc binding site
717Q, 720H, 820D, 879H
CDD
cd06572 (Histidinol_dh)

720H

zinc binding site
717Q, 720H, 820D, 879H
CDD
cd06572 (Histidinol_dh)

820D

zinc binding site
717Q, 720H, 820D, 879H
CDD
cd06572 (Histidinol_dh)

879H

zinc binding site
717Q, 720H, 820D, 879H
CDD
cd06572 (Histidinol_dh)
catalytic residues...

786E

catalytic residues
786E, 787H
CDD
cd06572 (Histidinol_dh)

787H

catalytic residues
786E, 787H
CDD
cd06572 (Histidinol_dh)

GO term prediction

Biological Process

GO:0000105 histidine biosynthetic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004399 histidinol dehydrogenase activity
GO:0004635 phosphoribosyl-AMP cyclohydrolase activity
GO:0004636 phosphoribosyl-ATP diphosphatase activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0051287 NAD binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features