GBC43557.1

Protein

Length

438 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
33 - 438
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 438

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  52 - 383
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  47 - 438
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  48 - 378
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  33 - 387
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR005829

Sugar transporter, conserved site
1. PS00217 (SUGAR_TRAN...)
  
  143 - 168
  
  PROSITE patterns
  PS00217 (SUGAR_TRANSPORT_2)

no IPR

Unintegrated signatures

Coil

407 - 434

COILS
Coil (Coil)
mobidb-lite (disord...)

1 - 28

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

62Y

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

65V

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

66V

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

67F

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

69I

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

70P

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

87I

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

90T

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

91L

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

94R

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

98A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

99A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

101F

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

102G

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

148M

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

149G

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

152W

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

153G

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

156A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

157A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

160M

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

172S

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

173G

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

176Q

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

177Q

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

183Y

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

266N

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

269S

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

270H

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

273Q

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

274D

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

277P

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

291V

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

295T

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

299N

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

302A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

306G

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

353Y

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

356V

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

357Q

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

360W

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

364P

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

365A

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

368N

putative substrate translocation pore
62Y, 65V, 66V, 67F, 69I, 70P, 87I, 90T, 91L, 94R, 98A, 99A, 101F, 102G, 148M, 149G, 152W, 153G, 156A, 157A, 160M, 172S, 173G, 176Q, 177Q, 183Y, 266N, 269S, 270H, 273Q, 274D, 277P, 291V, 295T, 299N, 302A, 306G, 353Y, 356V, 357Q, 360W, 364P, 365A, 368N
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features