GBC43548.1

Protein

Length

476 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 179
Class I glutamine amidotransferase-like (IPR029062)
Glutamine amidotransferase (IPR017926)
Domain
150 - 351
NAD/GMP synthase (IPR022310)
GMP synthetase ATP pyrophosphatase domain (IPR025777)
Domain
155 - 476
GMP synthase, C-terminal (IPR001674)

1 50 100 150 200 250 300 350 400 450 476

Detailed signature matches

IPR029062

Class I glutamine amidotransferase-like
1. SSF52317 (Class I g...)
  
  14 - 179
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR017926

Glutamine amidotransferase
1. PF00117 (GATase)
  
  37 - 142
  
  Pfam
  PF00117 (GATase)
2. PS51273 (GATASE_TYPE_1)
  
  1 - 149
  
  PROSITE profiles
  PS51273 (GATASE_TYPE_1)
IPR025777

GMP synthetase ATP pyrophosphatase domain
1. PS51553 (GMPS_ATP_P...)
  
  150 - 351
  
  PROSITE profiles
  PS51553 (GMPS_ATP_PPASE)
IPR001674

GMP synthase, C-terminal
1. PF00958 (GMP_synt_C)
  
  384 - 474
  
  Pfam
  PF00958 (GMP_synt_C)
2. TIGR00884
  
  155 - 476
  
  TIGRFAMs
  TIGR00884 (TIGR00884)
3. cd01997 (GMP_syntha...)
  
  172 - 474
  
  CDD
  cd01997 (GMP_synthase_C)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  169 - 238
  
  Pfam
  PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

SSF52402 (Adenine n...)

135 - 397

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
SSF54810 (GMP synth...)

356 - 476

SUPERFAMILY
SSF54810 (GMP synthetase C-terminal dimerisation domain)

Residue annotation

ATP Binding subdom...

172Q

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

173V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

174V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

175G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

176A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

177V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

178S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

179G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

180G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

181V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

182D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

183S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

184T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

185V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

186A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

187A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

188R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

189L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

190M

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

191K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

192E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

193A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

194I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

195G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

196D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

198F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

199H

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

200A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

201I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

202L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

203V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

204D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

205N

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

206G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

207L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

208M

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

210L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

211N

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

212E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

213C

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

214E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

215T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

216V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

217K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

218K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

219N

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

220L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

231V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

232D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

233A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

234S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

235E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

236I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

237F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

238L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

239D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

240R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

241L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

242K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

243G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

244V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

245T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

246D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

247P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

248E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

249K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

250K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

251R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

252K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

253I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

254I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

255G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

256N

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

257T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

258F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

259I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

260E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

261V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

262F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

263E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

264S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

265E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

266A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

267L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

268K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

283Y

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

284L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

285L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

286Q

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

287G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

288T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

289L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

290Y

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

291P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

292D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

293V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

294I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

295E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

296S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

297V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

298S

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

307K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

308T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

309H

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

310H

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

311N

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

312V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

313G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

314G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

315L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

316L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

321L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

322K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

323L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

324I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

325E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

326P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

327L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

328R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

329E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

330L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

331F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

332K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

333D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

334E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

335V

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

336R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

337E

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

338L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

339G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

340K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

341T

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

342L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

343K

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

344L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

345D

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

351R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

352H

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

353P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

354F

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

355P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

356G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

357P

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

358G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

359I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

360A

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

361I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

362R

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

363I

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

364L

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)

365G

ATP Binding subdomain
172Q, 173V, 174V, 175G, 176A, 177V, 178S, 179G, 180G, 181V, 182D, 183S, 184T, 185V, 186A, 187A, 188R, 189L, 190M, 191K, 192E, 193A, 194I, 195G, 196D, 198F, 199H, 200A, 201I, 202L, 203V, 204D, 205N, 206G, 207L, 208M, 210L, 211N, 212E, 213C, 214E, 215T, 216V, 217K, 218K, 219N, 220L, 231V, 232D, 233A, 234S, 235E, 236I, 237F, 238L, 239D, 240R, 241L, 242K, 243G, 244V, 245T, 246D, 247P, 248E, 249K, 250K, 251R, 252K, 253I, 254I, 255G, 256N, 257T, 258F, 259I, 260E, 261V, 262F, 263E, 264S, 265E, 266A, 267L, 268K, 283Y, 284L, 285L, 286Q, 287G, 288T, 289L, 290Y, 291P, 292D, 293V, 294I, 295E, 296S, 297V, 298S, 307K, 308T, 309H, 310H, 311N, 312V, 313G, 314G, 315L, 316L, 321L, 322K, 323L, 324I, 325E, 326P, 327L, 328R, 329E, 330L, 331F, 332K, 333D, 334E, 335V, 336R, 337E, 338L, 339G, 340K, 341T, 342L, 343K, 344L, 345D, 351R, 352H, 353P, 354F, 355P, 356G, 357P, 358G, 359I, 360A, 361I, 362R, 363I, 364L, 365G
CDD
cd01997 (GMP_synthase_C)
Ligand Binding sit...

176A

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

177V

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

178S

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

180G

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

181V

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

182D

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

183S

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

201I

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

203V

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)

332K

Ligand Binding sites
176A, 177V, 178S, 180G, 181V, 182D, 183S, 201I, 203V, 332K
CDD
cd01997 (GMP_synthase_C)
Dimerization subdo...

374I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

375V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

376R

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

377A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

378A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

379D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

380H

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

381I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

382Y

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

383I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

384D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

385E

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

386I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

395I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

396S

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

397Q

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

398A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

399Y

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

400A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

401A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

402L

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

403L

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

404P

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

407A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

408V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

409G

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

410V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

411M

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

412G

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

413D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

414K

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

415R

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

416T

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

417Y

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

421I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

422T

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

423L

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

424R

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

425A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

426V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

427E

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

428T

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

429V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

430D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

431F

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

432M

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

433T

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

434A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

435D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

436W

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

443V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

444L

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

445K

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

446K

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

447I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

448S

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

449N

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

450R

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

451I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

453N

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

454E

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

455V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

456K

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

457G

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

458V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

459N

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

460R

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

461V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

462V

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

463Y

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

464D

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

465I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

466S

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

467S

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

468K

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

469P

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

470P

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

471A

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

472T

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

473I

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

474E

Dimerization subdomain
374I, 375V, 376R, 377A, 378A, 379D, 380H, 381I, 382Y, 383I, 384D, 385E, 386I, 395I, 396S, 397Q, 398A, 399Y, 400A, 401A, 402L, 403L, 404P, 407A, 408V, 409G, 410V, 411M, 412G, 413D, 414K, 415R, 416T, 417Y, 421I, 422T, 423L, 424R, 425A, 426V, 427E, 428T, 429V, 430D, 431F, 432M, 433T, 434A, 435D, 436W, 443V, 444L, 445K, 446K, 447I, 448S, 449N, 450R, 451I, 453N, 454E, 455V, 456K, 457G, 458V, 459N, 460R, 461V, 462V, 463Y, 464D, 465I, 466S, 467S, 468K, 469P, 470P, 471A, 472T, 473I, 474E
CDD
cd01997 (GMP_synthase_C)

GO term prediction

Biological Process

GO:0006164 purine nucleotide biosynthetic process
GO:0006177 GMP biosynthetic process

Molecular Function

GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016462 pyrophosphatase activity

Cellular Component