GBC38220.1

Protein

Length

1,822 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
728 - 830
Retrotransposon gag domain (IPR005162)
915 - 955
Zinc finger, CCHC-type (IPR001878)
1,101 - 1,128
Zinc finger, CCHC-type (IPR001878)
1,207 - 1,302
Aspartic peptidase domain (IPR021109)
1,429 - 1,608
Reverse transcriptase domain (IPR000477)

1 200 400 600 800 1000 1200 1400 1600 1822

Detailed signature matches

IPR005162

Retrotransposon gag domain
1. PF03732 (Retrotrans...)
  
  728 - 830
  
  Pfam
  PF03732 (Retrotrans_gag)
IPR001878

Zinc finger, CCHC-type
1. PS50158 (ZF_CCHC)
  
  936 - 950
  
  PROSITE profiles
  PS50158 (ZF_CCHC)
  
  1,113 - 1,128
  
  PROSITE profiles
  PS50158 (ZF_CCHC)
2. PF00098 (zf-CCHC)
  
  934 - 950
  
  Pfam
  PF00098 (zf-CCHC)
  
  1,112 - 1,128
  
  Pfam
  PF00098 (zf-CCHC)
3. SM00343 (c2hcfinal6)
  
  935 - 951
  
  SMART
  SM00343 (c2hcfinal6)
  
  1,112 - 1,128
  
  SMART
  SM00343 (c2hcfinal6)
4. SSF57756 (Retroviru...)
  
  1,101 - 1,128
  
  SUPERFAMILY
  SSF57756 (Retrovirus zinc finger-like domains)
  
  915 - 955
  
  SUPERFAMILY
  SSF57756 (Retrovirus zinc finger-like domains)
IPR021109

Aspartic peptidase domain
1. SSF50630 (Acid prot...)
  
  1,207 - 1,302
  
  SUPERFAMILY
  SSF50630 (Acid proteases)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,450 - 1,607
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,429 - 1,608
  
  PROSITE profiles
  PS50878 (RT_POL)

no IPR

Unintegrated signatures

Coil

376 - 396

COILS
Coil (Coil)

514 - 534

COILS
Coil (Coil)
SSF56672 (DNA/RNA p...)

1,373 - 1,807

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd00303 (retropepsi...)

1,207 - 1,290

CDD
cd00303 (retropepsin_like)
cd01647 (RT_LTR)

1,432 - 1,608

CDD
cd01647 (RT_LTR)
cd09274 (RNase_HI_R...)

1,702 - 1,821

CDD
cd09274 (RNase_HI_RT_Ty3)
mobidb-lite (disord...)

541 - 608

MobiDB Lite
mobidb-lite (disorder_prediction)

915 - 938

MobiDB Lite
mobidb-lite (disorder_prediction)

950 - 993

MobiDB Lite
mobidb-lite (disorder_prediction)

1,049 - 1,089

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Catalytic residue ...

1,220D

Catalytic residue
1,220D
CDD
cd00303 (retropepsin_like)
catalytic motif cd...

1,220D

catalytic motif
1,220D, 1,221T, 1,222G
CDD
cd00303 (retropepsin_like)

1,221T

catalytic motif
1,220D, 1,221T, 1,222G
CDD
cd00303 (retropepsin_like)

1,222G

catalytic motif
1,220D, 1,221T, 1,222G
CDD
cd00303 (retropepsin_like)
inhibitor binding ...

1,220D

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)

1,222G

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)

1,224A

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)

1,249V

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)

1,250M

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)

1,288V

inhibitor binding site
1,220D, 1,222G, 1,224A, 1,249V, 1,250M, 1,288V
CDD
cd00303 (retropepsin_like)
Active site flap c...

1,249V

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,250M

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,251I

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,255K

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,256L

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,257A

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)

1,258S

Active site flap
1,249V, 1,250M, 1,251I, 1,255K, 1,256L, 1,257A, 1,258S
CDD
cd00303 (retropepsin_like)
putative NTP bindi...

1,495D

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,496L

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,497A

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,498S

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,499G

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,500F

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,529F

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)

1,559D

putative NTP binding site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,559D
CDD
cd01647 (RT_LTR)
putative active si...

1,495D

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,496L

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,497A

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,498S

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,499G

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,500F

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,529F

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,530G

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,557Y

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,559D

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,560D

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,604L

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)

1,605G

putative active site
1,495D, 1,496L, 1,497A, 1,498S, 1,499G, 1,500F, 1,529F, 1,530G, 1,557Y, 1,559D, 1,560D, 1,604L, 1,605G
CDD
cd01647 (RT_LTR)
putative nucleic a...

1,530G

putative nucleic acid binding site
1,530G
CDD
cd01647 (RT_LTR)
active site cd09274

1,706D

active site
1,706D, 1,748E, 1,773D, 1,816D
CDD
cd09274 (RNase_HI_RT_Ty3)

1,748E

active site
1,706D, 1,748E, 1,773D, 1,816D
CDD
cd09274 (RNase_HI_RT_Ty3)

1,773D

active site
1,706D, 1,748E, 1,773D, 1,816D
CDD
cd09274 (RNase_HI_RT_Ty3)

1,816D

active site
1,706D, 1,748E, 1,773D, 1,816D
CDD
cd09274 (RNase_HI_RT_Ty3)
RNA/DNA hybrid bin...

1,706D

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,707A

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,708S

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,709G

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,743P

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,744I

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,745T

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,748E

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,773D

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,806H

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,820R

RNA/DNA hybrid binding site
1,706D, 1,707A, 1,708S, 1,709G, 1,743P, 1,744I, 1,745T, 1,748E, 1,773D, 1,806H, 1,820R
CDD
cd09274 (RNase_HI_RT_Ty3)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

GBC38220.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component