GBC32995.1

Protein

Length

644 amino acids

Protein family membership

Aspartyl/Asparaginyl-tRNA synthetase, class IIb (IPR002312)
- Aspartate-tRNA ligase, type 1 (IPR004524)

Domains and repeats

Domain
33 - 160
Nucleic acid-binding, OB-fold (IPR012340)
170 - 624
Aminoacyl-tRNA synthetase, class II (IPR006195)
Aminoacyl-tRNA synthetase, class II (D/K/N) (IPR004364)

1 100 200 300 400 500 644

Detailed signature matches

IPR002312

Aspartyl/Asparaginyl-tRNA synthetase, class IIb
1. PR01042 (TRNASYNTHASP)
  
  259 - 272
  
  PRINTS
  PR01042 (TRNASYNTHASP)
  
  242 - 254
  
  PRINTS
  PR01042 (TRNASYNTHASP)
  
  574 - 588
  
  PRINTS
  PR01042 (TRNASYNTHASP)
  
  530 - 546
  
  PRINTS
  PR01042 (TRNASYNTHASP)
IPR004524

Aspartate-tRNA ligase, type 1
1. TIGR00459
  
  46 - 639
  
  TIGRFAMs
  TIGR00459 (TIGR00459)
2. MF_00044 (Asp_tRNA_...)
  
  45 - 640
  
  HAMAP
  MF_00044 (Asp_tRNA_synth_type1)
IPR012340

Nucleic acid-binding, OB-fold
1. SSF50249 (Nucleic a...)
  
  33 - 160
  
  SUPERFAMILY
  SSF50249 (Nucleic acid-binding proteins)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  201 - 624
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)
IPR004364

Aminoacyl-tRNA synthetase, class II (D/K/N)
1. PF00152 (tRNA-synt_2)
  
  170 - 613
  
  Pfam
  PF00152 (tRNA-synt_2)

no IPR

Unintegrated signatures

SSF55681 (Class II ...)

480 - 641

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)

159 - 346

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)
cd00777 (AspRS_core)

191 - 615

CDD
cd00777 (AspRS_core)
cd04317 (EcAspRS_li...)

46 - 187

CDD
cd04317 (EcAspRS_like_N)

Residue annotation

dimer interface cd...

46R

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

49T

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

67W

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

86S

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

154N

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

156A

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)

157N

dimer interface
46R, 49T, 67W, 86S, 154N, 156A, 157N
CDD
cd04317 (EcAspRS_like_N)
anticodon binding ...

70R

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

72R

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

73K

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

74L

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

80F

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

91Q

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

115S

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

129R

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

135N

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

144E

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)

160P

anticodon binding site
70R, 72R, 73K, 74L, 80F, 91Q, 115S, 129R, 135N, 144E, 160P
CDD
cd04317 (EcAspRS_like_N)
homodimer interfac...

194R

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

195S

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

196L

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

199W

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

202R

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

203D

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

206V

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

209G

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

210F

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

211V

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

212E

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

214E

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

215T

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

216P

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

217I

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

218L

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

219F

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

220K

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

227R

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

230I

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

231V

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

232P

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

233T

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

234R

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

237G

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

238L

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

239F

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

240Y

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

255V

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

256G

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

259D

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

260K

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

266K

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

270D

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

280E

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

290F

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

295D

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

572H

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

575N

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

576A

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

578G

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

579H

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

580G

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

581C

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

609A

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

610F

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)

612K

homodimer interface
194R, 195S, 196L, 199W, 202R, 203D, 206V, 209G, 210F, 211V, 212E, 214E, 215T, 216P, 217I, 218L, 219F, 220K, 227R, 230I, 231V, 232P, 233T, 234R, 237G, 238L, 239F, 240Y, 255V, 256G, 259D, 260K, 266K, 270D, 280E, 290F, 295D, 572H, 575N, 576A, 578G, 579H, 580G, 581C, 609A, 610F, 612K
CDD
cd00777 (AspRS_core)
motif 1 cd00777

216P

motif 1
216P, 217I, 218L, 219F, 220K
CDD
cd00777 (AspRS_core)

217I

motif 1
216P, 217I, 218L, 219F, 220K
CDD
cd00777 (AspRS_core)

218L

motif 1
216P, 217I, 218L, 219F, 220K
CDD
cd00777 (AspRS_core)

219F

motif 1
216P, 217I, 218L, 219F, 220K
CDD
cd00777 (AspRS_core)

220K

motif 1
216P, 217I, 218L, 219F, 220K
CDD
cd00777 (AspRS_core)
active site cd00777

224E

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

225G

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

226A

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

245S

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

247Q

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

250K

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

269R

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

271E

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

276D

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

277R

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

278Q

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

281F

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

283Q

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

504H

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

505H

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

538E

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

541G

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

545R

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

587I

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

588A

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

590G

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)

593R

active site
224E, 225G, 226A, 245S, 247Q, 250K, 269R, 271E, 276D, 277R, 278Q, 281F, 283Q, 504H, 505H, 538E, 541G, 545R, 587I, 588A, 590G, 593R
CDD
cd00777 (AspRS_core)
motif 2 cd00777

268F

motif 2
268F, 269R, 270D, 271E
CDD
cd00777 (AspRS_core)

269R

motif 2
268F, 269R, 270D, 271E
CDD
cd00777 (AspRS_core)

270D

motif 2
268F, 269R, 270D, 271E
CDD
cd00777 (AspRS_core)

271E

motif 2
268F, 269R, 270D, 271E
CDD
cd00777 (AspRS_core)
motif 3 cd00777

590G

motif 3
590G, 591F, 592D, 593R
CDD
cd00777 (AspRS_core)

591F

motif 3
590G, 591F, 592D, 593R
CDD
cd00777 (AspRS_core)

592D

motif 3
590G, 591F, 592D, 593R
CDD
cd00777 (AspRS_core)

593R

motif 3
590G, 591F, 592D, 593R
CDD
cd00777 (AspRS_core)

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features