Protein

GBC27405.1

Length
1,630 amino acids

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1630

Detailed signature matches

  1. Family IPR016255
    eIF-2-alpha kinase Gcn2
    1. PIRSF000660 (STPK_GCN2)
  2. Domain IPR016135
    Ubiquitin-conjugating enzyme/RWD-like
    1. SSF54495 (UBC-like)
  3. Domain IPR006575
    RWD domain
    1. PS50908 (RWD)
    2. SM00591 (RWD2001b)
    3. PF05773 (RWD)
  4. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  5. Domain IPR000719
    Protein kinase domain
    1. SM00220 (serkin_6)
    2. PS50011 (PROTEIN_KI...)
    3. PF00069 (Pkinase)
  6. Domain IPR024435
    Histidyl tRNA synthetase-related domain
    1. PF12745 (HGTP_antic...)
  7. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
  8. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. PF13393 (tRNA-synt_His)
  3. SSF55681 (Class II ...)
  4. cd14012 (PK_eIF2AK_...)
  5. cd14046 (STKc_EIF2A...)
  6. mobidb-lite (disord...)

Residue annotation

  1. dimer interface cd...
  2. ATP binding site c...
  3. active site cd14046
  4. activation loop (A...
  5. eIF2alpha (substra...

GO term prediction

Biological Process

GO:0000077 DNA damage checkpoint
GO:0006468 protein phosphorylation
GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

None predicted.