GBC26350.1

Protein

Length

381 amino acids

Protein family membership

Adenosylhomocysteinase-like (IPR000043)

Domains and repeats

Domain
140 - 301
S-adenosyl-L-homocysteine hydrolase, NAD binding domain (IPR015878)
Domain
140 - 301
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 350 381

Detailed signature matches

IPR000043

Adenosylhomocysteinase-like
1. PF05221 (AdoHcyase)
  
  3 - 45
  
  Pfam
  PF05221 (AdoHcyase)
  
  90 - 380
  
  Pfam
  PF05221 (AdoHcyase)
2. SM00996 (AdoHcyase_2)
  
  3 - 380
  
  SMART
  SM00996 (AdoHcyase_2)
3. PIRSF001109 (SAHH)
  
  61 - 381
  
  PIRSF
  PIRSF001109 (SAHH)
4. cd00401 (SAHH)
  
  13 - 369
  
  CDD
  cd00401 (SAHH)
IPR015878

S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1. SM00997 (AdoHcyase_...)
  
  140 - 301
  
  SMART
  SM00997 (AdoHcyase_NAD_2)
2. PF00670 (AdoHcyase_NAD)
  
  140 - 301
  
  Pfam
  PF00670 (AdoHcyase_NAD)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  140 - 301
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR020082

S-adenosyl-L-homocysteine hydrolase, conserved site
1. PS00739 (ADOHCYASE_2)
  
  162 - 179
  
  PROSITE patterns
  PS00739 (ADOHCYASE_2)

no IPR

Unintegrated signatures

SSF52283 (Formate/g...)

302 - 381

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)

2 - 139

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)

Residue annotation

homotetramer inter...

14W

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

17Q

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

21L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

24N

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

25E

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

111H

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

114Y

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

115K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

131D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

133V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

137K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

138F

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

142Y

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

145R

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

146E

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

150D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

153K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

154R

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

157D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

158V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

159H

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

160I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

161A

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

162G

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

163K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

171G

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

172D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

175K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

184I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

185G

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

187R

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

192E

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

193I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

194D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

195P

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

196I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

197N

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

198A

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

199L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

200Q

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

202A

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

203V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

204E

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

205G

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

207K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

208V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

209T

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

210T

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

213D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

226A

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

227N

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

228R

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

229D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

230I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

240K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

241D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

242D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

253V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

270I

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

271K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

276R

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

300T

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

303P

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

305F

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

306V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

309N

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

334M

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

340D

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

341E

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

344A

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

345T

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

348L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

351L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

352G

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

354K

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

355L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

356T

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

358L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

361V

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

362Q

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

365Y

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)

366L

homotetramer interface
14W, 17Q, 21L, 24N, 25E, 111H, 114Y, 115K, 131D, 133V, 137K, 138F, 142Y, 145R, 146E, 150D, 153K, 154R, 157D, 158V, 159H, 160I, 161A, 162G, 163K, 171G, 172D, 175K, 184I, 185G, 187R, 192E, 193I, 194D, 195P, 196I, 197N, 198A, 199L, 200Q, 202A, 203V, 204E, 205G, 207K, 208V, 209T, 210T, 213D, 226A, 227N, 228R, 229D, 230I, 240K, 241D, 242D, 253V, 270I, 271K, 276R, 300T, 303P, 305F, 306V, 309N, 334M, 340D, 341E, 344A, 345T, 348L, 351L, 352G, 354K, 355L, 356T, 358L, 361V, 362Q, 365Y, 366L
CDD
cd00401 (SAHH)
ligand binding sit...

80D

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

105E

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

106T

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

135K

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

139D

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

296L

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

301G

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

302H

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

307M

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)

311F

ligand binding site
80D, 105E, 106T, 135K, 139D, 296L, 301G, 302H, 307M, 311F
CDD
cd00401 (SAHH)
NAD binding site c...

106T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

107T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

108T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

140N

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

144C

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

169G

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

171G

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

172D

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

173V

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

191T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

192E

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

193I

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

194D

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

197N

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

224T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

225T

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

226A

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

227N

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

230I

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

248I

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

249G

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

250H

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

293L

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

295N

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

302H

NAD binding site
106T, 107T, 108T, 140N, 144C, 169G, 171G, 172D, 173V, 191T, 192E, 193I, 194D, 197N, 224T, 225T, 226A, 227N, 230I, 248I, 249G, 250H, 293L, 295N, 302H
CDD
cd00401 (SAHH)

GO term prediction

Biological Process

GO:0006730 one-carbon metabolic process

Molecular Function

GO:0004013 adenosylhomocysteinase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC26350.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component