GBC15654.1

Protein

Length

2,295 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
2 - 405
Armadillo-type fold (IPR016024)
349 - 756
Armadillo-type fold (IPR016024)
791 - 1,080
Armadillo-type fold (IPR016024)
1,115 - 1,338
Armadillo-type fold (IPR016024)
1,803 - 1,900
FKBP12-rapamycin binding domain (IPR009076)
2,263 - 2,295
FATC domain (IPR003152)
Domain
710 - 868
Domain of unknown function DUF3385, target of rapamycin protein (IPR024585)
1,215 - 1,770
PIK-related kinase (IPR014009)
PIK-related kinase, FAT (IPR003151)
1,885 - 2,295
Protein kinase-like domain (IPR011009)
Phosphatidylinositol 3-/4-kinase, catalytic domain (IPR000403)

1 500 1000 1500 2000 2295

Detailed signature matches

IPR016024

Armadillo-type fold
1. SSF48371 (ARM repeat)
  
  349 - 756
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,115 - 1,338
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  791 - 1,080
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  437 - 540
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  2 - 405
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
IPR024585

Domain of unknown function DUF3385, target of rapamycin protein
1. PF11865 (DUF3385)
  
  710 - 867
  
  Pfam
  PF11865 (DUF3385)
2. SM01346 (DUF3385_3)
  
  710 - 868
  
  SMART
  SM01346 (DUF3385_3)
IPR014009

PIK-related kinase
1. PS51189 (FAT)
  
  1,215 - 1,770
  
  PROSITE profiles
  PS51189 (FAT)
IPR003151

PIK-related kinase, FAT
1. PF02259 (FAT)
  
  1,349 - 1,696
  
  Pfam
  PF02259 (FAT)
IPR009076

FKBP12-rapamycin binding domain
1. PF08771 (FRB_dom)
  
  1,803 - 1,900
  
  Pfam
  PF08771 (FRB_dom)
2. SSF47212 (FKBP12-ra...)
  
  1,807 - 1,899
  
  SUPERFAMILY
  SSF47212 (FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP))
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  2,082 - 2,217
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  1,885 - 2,047
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000403

Phosphatidylinositol 3-/4-kinase, catalytic domain
1. SM00146 (pi3k_hr1_6)
  
  1,971 - 2,284
  
  SMART
  SM00146 (pi3k_hr1_6)
2. PS50290 (PI3_4_KINA...)
  
  1,970 - 2,295
  
  PROSITE profiles
  PS50290 (PI3_4_KINASE_3)
3. PF00454 (PI3_PI4_ki...)
  
  1,970 - 2,219
  
  Pfam
  PF00454 (PI3_PI4_kinase)
IPR003152

FATC domain
1. SM01343 (FATC_2)
  
  2,263 - 2,295
  
  SMART
  SM01343 (FATC_2)
2. PF02260 (FATC)
  
  2,265 - 2,295
  
  Pfam
  PF02260 (FATC)
3. PS51190 (FATC)
  
  2,263 - 2,295
  
  PROSITE profiles
  PS51190 (FATC)
IPR018936

Phosphatidylinositol 3/4-kinase, conserved site
1. PS00916 (PI3_4_KINA...)
  
  2,111 - 2,131
  
  PROSITE patterns
  PS00916 (PI3_4_KINASE_2)
2. PS00915 (PI3_4_KINA...)
  
  1,974 - 1,988
  
  PROSITE patterns
  PS00915 (PI3_4_KINASE_1)

no IPR

Unintegrated signatures

Coil

536 - 556

COILS
Coil (Coil)

1,281 - 1,301

COILS
Coil (Coil)
PF13513 (HEAT_EZ)

654 - 703

Pfam
PF13513 (HEAT_EZ)
SM01345 (Rapamycin_...)

1,803 - 1,902

SMART
SM01345 (Rapamycin_bind_3)
cd00020 (ARM)

594 - 705

CDD
cd00020 (ARM)
cd05169 (PIKKc_TOR)

1,941 - 2,219

CDD
cd05169 (PIKKc_TOR)
mobidb-lite (disord...)

1,071 - 1,090

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

protein binding su...

611E

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

615R

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

619L

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

649A

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

653S

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

656A

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

660E

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

695A

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

698K

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

701G

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

702Q

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)

705S

protein binding surface
611E, 615R, 619L, 649A, 653S, 656A, 660E, 695A, 698K, 701G, 702Q, 705S
CDD
cd00020 (ARM)
ATP binding site c...

1,951I

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,953S

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,954K

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,955Q

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,957P

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,973L

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,975K

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

1,978E

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,013Y

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,025L

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,026G

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,027W

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,028V

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,033T

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,131N

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,133M

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,144I

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)

2,145D

ATP binding site
1,951I, 1,953S, 1,954K, 1,955Q, 1,957P, 1,973L, 1,975K, 1,978E, 2,013Y, 2,025L, 2,026G, 2,027W, 2,028V, 2,033T, 2,131N, 2,133M, 2,144I, 2,145D
CDD
cd05169 (PIKKc_TOR)
mLST8 interface cd...

2,060A

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,061P

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,062D

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,065Q

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,066C

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,067T

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,068I

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,070E

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,072V

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,073E

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)

2,076E

mLST8 interface
2,060A, 2,061P, 2,062D, 2,065Q, 2,066C, 2,067T, 2,068I, 2,070E, 2,072V, 2,073E, 2,076E
CDD
cd05169 (PIKKc_TOR)
catalytic loop cd0...

2,123G

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,124L

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,125G

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,126D

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,127R

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,128H

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,129P

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,130S

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)

2,131N

catalytic loop
2,123G, 2,124L, 2,125G, 2,126D, 2,127R, 2,128H, 2,129P, 2,130S, 2,131N
CDD
cd05169 (PIKKc_TOR)
activation loop (A...

2,145D

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,146F

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,147G

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,148D

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,149C

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,150F

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,151E

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,152V

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,153A

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,154M

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,155T

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,156R

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,157E

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,158K

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,159Y

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,160P

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,161E

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,162K

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,163I

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,164P

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,165F

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,166R

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,167L

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

2,168T

activation loop (A-loop)
2,145D, 2,146F, 2,147G, 2,148D, 2,149C, 2,150F, 2,151E, 2,152V, 2,153A, 2,154M, 2,155T, 2,156R, 2,157E, 2,158K, 2,159Y, 2,160P, 2,161E, 2,162K, 2,163I, 2,164P, 2,165F, 2,166R, 2,167L, 2,168T
CDD
cd05169 (PIKKc_TOR)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0016301 kinase activity
GO:0044877 macromolecular complex binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC15654.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component