GBC13511.1

Protein

Length

611 amino acids

Protein family membership

AP endonuclease 1 (IPR004808)

Domains and repeats

Domain
1 - 301
Endonuclease/exonuclease/phosphatase (IPR005135)
536 - 582
Zinc finger, GRF-type (IPR010666)

1 100 200 300 400 500 611

Detailed signature matches

IPR004808

AP endonuclease 1
1. PS51435 (AP_NUCLEAS...)
  
  1 - 303
  
  PROSITE profiles
  PS51435 (AP_NUCLEASE_F1_4)
2. TIGR00633
  
  1 - 301
  
  TIGRFAMs
  TIGR00633 (TIGR00633)
IPR005135

Endonuclease/exonuclease/phosphatase
1. PF03372 (Exo_endo_phos)
  
  4 - 294
  
  Pfam
  PF03372 (Exo_endo_phos)
2. SSF56219 (DNase I-like)
  
  131 - 301
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
  
  1 - 83
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
IPR010666

Zinc finger, GRF-type
1. PF06839 (zf-GRF)
  
  536 - 582
  
  Pfam
  PF06839 (zf-GRF)
IPR020848

AP endonuclease 1, conserved site
1. PS00728 (AP_NUCLEAS...)
  
  262 - 273
  
  PROSITE patterns
  PS00728 (AP_NUCLEASE_F1_3)

no IPR

Unintegrated signatures

cd09088 (Ape2-like_...)

2 - 301

CDD
cd09088 (Ape2-like_AP-endo)

Residue annotation

putative DNA bindi...

7N

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

9N

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

10G

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

11I

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

12R

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

13S

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

14I

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

42E

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

44K

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

48D

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

72G

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

73Y

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

136R

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

151Y

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

154H

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

156S

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

160R

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

190D

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

202D

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

204Q

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

206S

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

251C

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

253N

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

254T

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

255L

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

261I

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

263Y

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

265T

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

267L

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

291G

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative DNA binding site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 261I, 263Y, 265T, 267L, 291G, 294H
CDD
cd09088 (Ape2-like_AP-endo)
putative catalytic...

7N

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

42E

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

151Y

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

190D

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

268D

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

293D

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative catalytic site
7N, 42E, 151Y, 190D, 192N, 268D, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)
putative active si...

7N

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

9N

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

10G

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

11I

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

12R

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

13S

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

14I

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

42E

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

44K

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

48D

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

72G

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

73Y

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

136R

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

151Y

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

154H

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

156S

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

160R

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

190D

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

202D

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

204Q

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

206S

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

251C

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

253N

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

254T

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

255L

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

257N

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

261I

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

263Y

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

265T

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

267L

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

268D

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

291G

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

293D

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative active site
7N, 9N, 10G, 11I, 12R, 13S, 14I, 42E, 44K, 48D, 72G, 73Y, 136R, 151Y, 154H, 156S, 160R, 190D, 192N, 202D, 204Q, 206S, 251C, 253N, 254T, 255L, 257N, 261I, 263Y, 265T, 267L, 268D, 291G, 293D, 294H
CDD
cd09088 (Ape2-like_AP-endo)
putative phosphate...

7N

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

42E

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

151Y

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

154H

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

190D

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative phosphate binding site
7N, 42E, 151Y, 154H, 190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)
putative metal bin...

9N

putative metal binding site A
9N, 42E, 293D
CDD
cd09088 (Ape2-like_AP-endo)

42E

putative metal binding site A
9N, 42E, 293D
CDD
cd09088 (Ape2-like_AP-endo)

293D

putative metal binding site A
9N, 42E, 293D
CDD
cd09088 (Ape2-like_AP-endo)
putative AP bindin...

151Y

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

154H

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

190D

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

251C

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

265T

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

267L

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative AP binding site
151Y, 154H, 190D, 192N, 251C, 265T, 267L, 294H
CDD
cd09088 (Ape2-like_AP-endo)
putative metal bin...

190D

putative metal binding site B
190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

192N

putative metal binding site B
190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

294H

putative metal binding site B
190D, 192N, 294H
CDD
cd09088 (Ape2-like_AP-endo)

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0008270 zinc ion binding

Cellular Component

GO:0005622 intracellular

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Entry type

Status

Per-residue features